Astrid M Westendorf
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Explore the profile of Astrid M Westendorf including associated specialties, affiliations and a list of published articles.
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111
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4716
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Recent Articles
1.
Wenzek C, Siemes D, Hones G, Pastille E, Harting N, Kaiser F, et al.
iScience
. 2024 Aug;
27(8):110547.
PMID: 39175769
The immune system has emerged as an important target of thyroid hormones (THs); however, the role of TH in T cells has so far remained elusive. In this study, we...
2.
Mekes-Adamczyk A, Gausmann N, Oznur O, Pfuhlmann K, Dziobaka J, Buer J, et al.
Inflamm Bowel Dis
. 2024 Aug;
31(1):200-209.
PMID: 39102712
Background: Crohn's disease (CD) significantly affects patients' well-being and is influenced by stress and lifestyle factors, highlighting the importance of improving quality of life in CD management. An imbalance between...
3.
Ninnemann A, Hock K, Luppus S, Scherbaum N, Temme C, Buer J, et al.
Int Immunopharmacol
. 2024 Aug;
140:112736.
PMID: 39088925
Opioid addiction presents a relevant health challenge, with chronic heroin use linked to detrimental effects on various aspects of physical, mental, and sociological health. Opioid maintenance therapy (OMT), particularly using...
4.
Wachtendorf S, Jonin F, Ochel A, Heinrich F, Westendorf A, Tiegs G, et al.
Front Immunol
. 2024 Apr;
15:1351405.
PMID: 38571949
Introduction: The alarmin IL-33 has been implicated in the pathology of immune-mediated liver diseases. IL-33 activates regulatory T cells (Tregs) and type 2 innate lymphoid cells (ILC2s) expressing the IL-33...
5.
Influenza virus infection enhances tumour-specific CD8+ T-cell immunity, facilitating tumour control
Steinbach P, Pastille E, Kaumanns L, Adamczyk A, Sutter K, Hansen W, et al.
PLoS Pathog
. 2024 Jan;
20(1):e1011982.
PMID: 38271469
Influenza A virus (IAV) can cause severe respiratory infection leading to significant global morbidity and mortality through seasonal epidemics. Likewise, the constantly increasing number of cancer diseases is a growing...
6.
Abberger H, Hose M, Ninnemann A, Menne C, Eilbrecht M, Lang K, et al.
PLoS Pathog
. 2023 Nov;
19(11):e1011837.
PMID: 38019895
Neuropilin-1 (Nrp-1) expression on CD8+ T cells has been identified in tumor-infiltrating lymphocytes and in persistent murine gamma-herpes virus infections, where it interferes with the development of long-lived memory T...
7.
Buys W, Bick A, Madel R, Westendorf A, Buer J, Herbstreit F, et al.
Front Immunol
. 2023 Oct;
14:1277033.
PMID: 37869001
Introduction: Early sepsis is a life-threatening immune dysregulation believed to feature a "cytokine storm" due to activation of pattern recognition receptors by pathogen and danger associated molecular patterns. However, treatments...
8.
Haj-Yehia E, Korste S, Jochem R, Lusha A, Roth A, Dietzel N, et al.
Int J Cardiol Heart Vasc
. 2023 Sep;
48:101269.
PMID: 37731517
CD47 is a cell surface protein controlling phagocytotic activity of innate immune cells. CD47 blockade was investigated as an immune checkpoint therapy in cancer treatment, enhancing phagocytosis of tumor cells...
9.
Madel R, Borger V, Dittrich R, Bremer M, Tertel T, Phuong N, et al.
Cytotherapy
. 2023 Apr;
25(8):821-836.
PMID: 37055321
Background Aims: Extracellular vesicles (EVs) harvested from conditioned media of human mesenchymal stromal cells (MSCs) suppress acute inflammation in various disease models and promote regeneration of damaged tissues. After successful...
10.
Reuter S, Raspe J, Uebner H, Contoyannis A, Pastille E, Westendorf A, et al.
Front Immunol
. 2023 Feb;
14:1092801.
PMID: 36761723
Background: Asthma is an incurable heterogeneous disease with variations in clinical and underlying immunological phenotype. New approaches could help to support existing therapy concepts. Neonatal infection of mice with or...