Astrid M Westendorf
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Explore the profile of Astrid M Westendorf including associated specialties, affiliations and a list of published articles.
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111
Citations
4716
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Recent Articles
11.
Le-Trilling V, Jagnjic A, Brizic I, Eilbrecht M, Wohlgemuth K, Rozmanic C, et al.
NPJ Vaccines
. 2023 Feb;
8(1):8.
PMID: 36737485
Human cytomegalovirus (HCMV) frequently causes congenital infections, resulting in birth defects and developmental disorders. A vaccine is needed, but unavailable. We analyzed the potential of CMV mutants, lacking their STAT2...
12.
Frede A, Czarnewski P, Monasterio G, Tripathi K, Bejarano D, Ramirez Flores R, et al.
Immunity
. 2022 Dec;
55(12):2336-2351.e12.
PMID: 36462502
Therapeutic promotion of intestinal regeneration holds great promise, but defining the cellular mechanisms that influence tissue regeneration remains an unmet challenge. To gain insight into the process of mucosal healing,...
13.
Wenzek C, Steinbach P, Wirsdorfer F, Sutter K, Boehme J, Geffers R, et al.
iScience
. 2022 Nov;
25(12):105540.
PMID: 36437873
CD47 is an ubiquitously expressed surface molecule with significant impact on immune responses. However, its role for antiviral immunity is not fully understood. Here, we revealed that the expression of...
14.
Hose M, Gunther A, Naser E, Schumacher F, Schonberger T, Falkenstein J, et al.
Elife
. 2022 Nov;
11.
PMID: 36426850
Acid sphingomyelinase (Asm) and acid ceramidase (Ac) are parts of the sphingolipid metabolism. Asm hydrolyzes sphingomyelin to ceramide, which is further metabolized to sphingosine by Ac. Ceramide generates ceramide-enriched platforms...
15.
Le-Trilling V, Ebel J, Baier F, Wohlgemuth K, Pfeifer K, Mookhoek A, et al.
Eur J Immunol
. 2022 Oct;
53(2):e2249940.
PMID: 36250419
Primary and recurrent cytomegalovirus (CMV) infections frequently cause CMV colitis in immunocompromised as well as inflammatory bowel disease (IBD) patients. Additionally, colitis occasionally occurs upon primary CMV infection in patients...
16.
Gunther A, Hose M, Abberger H, Schumacher F, Veith Y, Kleuser B, et al.
Elife
. 2022 Sep;
11.
PMID: 36094170
Acid ceramidase (Ac) is part of the sphingolipid metabolism and responsible for the degradation of ceramide. As bioactive molecule, ceramide is involved in the regulation of many cellular processes. However,...
17.
Bick A, Buys W, Engler A, Madel R, Atia M, Faro F, et al.
PLoS One
. 2022 Aug;
17(8):e0273247.
PMID: 35981050
Rationale: The immune profile of sepsis patients is incompletely understood and hyperinflammation and hypoinflammation may occur concurrently or sequentially. Immune checkpoint inhibition (ICI) may counter hypoinflammation but effects are uncertain....
18.
Sokolova V, Ebel J, Kollenda S, Klein K, Kruse B, Veltkamp C, et al.
Small
. 2022 Jun;
18(31):e2201167.
PMID: 35712760
Ultrasmall gold nanoparticles (2 nm) easily penetrate the membranes of intestinal murine epithelial cells (MODE-K) and colorectal cancer cells (CT-26). They are also taken up by 3D spheroids (400 µm)...
19.
Reinold J, Farahpour F, Schoerding A, Fehring C, Dolff S, Konik M, et al.
Front Cell Infect Microbiol
. 2022 May;
12:848650.
PMID: 35521219
Clinical and experimental studies indicate that the bacterial and fungal gut microbiota modulates immune responses in distant organs including the lungs. Immune dysregulation is associated with severe SARS-CoV-2 infection, and...
20.
Wenzek C, Boelen A, Westendorf A, Engel D, Moeller L, Fuhrer D
Eur J Endocrinol
. 2022 Feb;
186(5):R65-R77.
PMID: 35175936
Over the past few years, growing evidence suggests direct crosstalk between thyroid hormones (THs) and the immune system. Components of the immune system were proposed to interfere with the central...