Astrid M van der Sar
Overview
Explore the profile of Astrid M van der Sar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
42
Citations
1498
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Schneider V, van Dijk A, van der Sar A, Kraaij M, Veldhuizen E, Haagsman H
Dev Comp Immunol
. 2016 Feb;
60:108-14.
PMID: 26920462
Chicken cathelicidin-2 (CATH-2) is a host defense peptide that exhibits immunomodulatory and antibacterial properties. Here we examined effects of CATH-2 in zebrafish embryos in the absence and presence of infection....
12.
Yoon S, Mitra S, Wyse C, Alnabulsi A, Zou J, Weerdenburg E, et al.
PLoS One
. 2015 Jun;
10(6):e0126378.
PMID: 26083432
Adaptive immunity in homeotherms depends greatly on CD4+ Th cells which release cytokines in response to specific antigen stimulation. Whilst bony fish and poikilothermic tetrapods possess cells that express TcR...
13.
Weerdenburg E, Abdallah A, Rangkuti F, Abd El Ghany M, Otto T, Adroub S, et al.
Infect Immun
. 2015 Feb;
83(5):1778-88.
PMID: 25690095
The interaction of environmental bacteria with unicellular eukaryotes is generally considered a major driving force for the evolution of intracellular pathogens, allowing them to survive and replicate in phagocytic cells...
14.
Torraca V, Cui C, Boland R, Bebelman J, van der Sar A, Smit M, et al.
Dis Model Mech
. 2015 Jan;
8(3):253-69.
PMID: 25573892
The recruitment of leukocytes to infectious foci depends strongly on the local release of chemoattractant mediators. The human CXC chemokine receptor 3 (CXCR3) is an important node in the chemokine...
15.
van Leeuwen L, van der Sar A, Bitter W
Cold Spring Harb Perspect Med
. 2014 Nov;
5(3):a018580.
PMID: 25414379
Over the past decade the zebrafish (Danio rerio) has become an attractive new vertebrate model organism for studying mycobacterial pathogenesis. The combination of medium-throughput screening and real-time in vivo visualization...
16.
van Leeuwen L, van der Kuip M, Youssef S, de Bruin A, Bitter W, Marceline van Furth A, et al.
Dis Model Mech
. 2014 Jul;
7(9):1111-22.
PMID: 24997190
Tuberculous meningitis (TBM) is one of the most severe extrapulmonary manifestations of tuberculosis, with a high morbidity and mortality. Characteristic pathological features of TBM are Rich foci, i.e. brain- and...
17.
Llamas M, van der Sar A
Methods Mol Biol
. 2014 May;
1149:709-21.
PMID: 24818945
In the last years, the zebrafish (Danio rerio) has become an important vertebrate animal model to study host-pathogen interactions, especially in its embryonic stage. The presence of a fully developed...
18.
Romano M, van de Weerd R, Brouwer F, Roviello G, Lacroix R, Sparrius M, et al.
Structure
. 2014 Apr;
22(5):719-30.
PMID: 24704253
The cell-envelope of Mycobacterium tuberculosis plays a key role in bacterial virulence and antibiotic resistance. Little is known about the molecular mechanisms of regulation of cell-envelope formation. Here, we elucidate...
19.
Makarov V, Lechartier B, Zhang M, Neres J, van der Sar A, Raadsen S, et al.
EMBO Mol Med
. 2014 Feb;
6(3):372-83.
PMID: 24500695
The benzothiazinone lead compound, BTZ043, kills Mycobacterium tuberculosis by inhibiting the essential flavo-enzyme DprE1, decaprenylphosphoryl-beta-D-ribose 2-epimerase. Here, we synthesized a new series of piperazine-containing benzothiazinones (PBTZ) and show that, like...
20.
van der Woude A, Stoop E, Stiess M, Wang S, Ummels R, van Stempvoort G, et al.
Cell Microbiol
. 2013 Oct;
16(2):280-95.
PMID: 24119166
The pathogenicity of mycobacteria is closely associated with their ability to export virulence factors. For this purpose, mycobacteria possess different protein secretion systems, including the accessory Sec translocation pathway, SecA2....