Astrid M van der Sar
Overview
Explore the profile of Astrid M van der Sar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
42
Citations
1498
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Niet S, van Zon M, de Punder K, Grootemaat A, Rutten S, Moorlag S, et al.
mSphere
. 2021 May;
6(3).
PMID: 33952660
infections claim more than a million lives each year, and better treatments or vaccines are required. A crucial pathogenicity factor is translocation from phagolysosomes to the cytosol upon phagocytosis by...
2.
van Dijk F, Semler O, Etich J, Kohler A, Jimenez-Estrada J, Bravenboer N, et al.
Am J Hum Genet
. 2020 Oct;
107(5):989-999.
PMID: 33053334
Osteogenesis imperfecta (OI) is characterized primarily by susceptibility to fractures with or without bone deformation. OI is genetically heterogeneous: over 20 genetic causes are recognized. We identified bi-allelic pathogenic KDELR2...
3.
Van Wijk R, van der Sar A, Krekels E, Verboom T, Spaink H, Simonsson U, et al.
Clin Transl Sci
. 2020 Apr;
13(6):1060-1064.
PMID: 32267997
The zebrafish infected with Mycobacterium marinum (M. marinum) is an attractive tuberculosis disease model, showing similar pathogenesis to Mycobacterium tuberculosis (M. tuberculosis) infections in humans. To translate pharmacological findings from...
4.
Burggraaf M, Speer A, Meijers A, Ummels R, van der Sar A, Korotkov K, et al.
mBio
. 2019 Oct;
10(5).
PMID: 31662454
Tuberculosis, one of the world's most severe infectious diseases, is caused by A major weapon of this pathogen is a unique cell wall that protects the pathogen from eradication by...
5.
CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity
Majolee J, Pronk M, Jim K, van Bezu J, van der Sar A, Hordijk P, et al.
Sci Rep
. 2019 Jun;
9(1):8131.
PMID: 31148579
RhoGTPases regulate cytoskeletal dynamics, migration and cell-cell adhesion in endothelial cells. Besides regulation at the level of guanine nucleotide binding, they also undergo post-translational modifications, for example ubiquitination. RhoGTPases are...
6.
Phan T, van Leeuwen L, Kuijl C, Ummels R, van Stempvoort G, Rubio-Canalejas A, et al.
PLoS Pathog
. 2018 Aug;
14(8):e1007247.
PMID: 30102741
The pathogen Mycobacterium tuberculosis employs a range of ESX-1 substrates to manipulate the host and build a successful infection. Although the importance of ESX-1 secretion in virulence is well established,...
7.
Bruinen A, Fisher G, Balez R, van der Sar A, Ooi L, Heeren R
J Am Soc Mass Spectrom
. 2018 Jun;
29(8):1571-1581.
PMID: 29949055
A unique method for identification of biomolecular components in different biological specimens, while preserving the capability for high speed 2D and 3D molecular imaging, is employed to investigate cellular response...
8.
van Leeuwen L, Boot M, Kuijl C, Picavet D, van Stempvoort G, van der Pol S, et al.
Cell Microbiol
. 2018 May;
20(9):e12858.
PMID: 29749044
Central nervous system (CNS) infection by Mycobacterium tuberculosis is one of the most devastating complications of tuberculosis, in particular in early childhood. In order to induce CNS infection, M. tuberculosis...
9.
Yoon S, Mitra S, Wyse C, Alnabulsi A, Zou J, Weerdenburg E, et al.
PLoS One
. 2016 Dec;
11(12):e0169149.
PMID: 28002434
[This corrects the article DOI: 10.1371/journal.pone.0126378.].
10.
Jim K, Engelen-Lee J, van der Sar A, Bitter W, Brouwer M, van der Ende A, et al.
J Neuroinflammation
. 2016 Aug;
13(1):188.
PMID: 27542968
Background: Streptococcus pneumoniae is one of the most important causes of bacterial meningitis, an infection where unfavourable outcome is driven by bacterial and host-derived toxins. In this study, we developed...