Asmaa Hachim
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Explore the profile of Asmaa Hachim including associated specialties, affiliations and a list of published articles.
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22
Citations
505
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Recent Articles
1.
Cheng S, Lau J, Tsang L, Leung K, Lee C, Hachim A, et al.
J Clin Virol
. 2023 Dec;
170:105621.
PMID: 38056114
Background: Natural SARS-CoV-2 infection may elicit antibodies to a range of viral proteins including non-structural protein ORF8. RNA, adenovirus vectored and sub-unit vaccines expressing SARS-CoV-2 spike would be only expected...
2.
Lau J, Cheng S, Leung K, Lee C, Hachim A, Tsang L, et al.
Nat Med
. 2023 Oct;
30(1):305.
PMID: 37875568
No abstract available.
3.
Teo Q, Wong H, Heunis T, Stancheva V, Hachim A, Lv H, et al.
Dev Cell
. 2023 Sep;
58(22):2495-2509.e6.
PMID: 37683630
Reprogramming lipid metabolic pathways is a critical feature of activating immune responses to infection. However, how these reconfigurations occur is poorly understood. Our previous screen to identify cellular deubiquitylases (DUBs)...
4.
Lau J, Cheng S, Leung K, Lee C, Hachim A, Tsang L, et al.
Nat Med
. 2023 Jan;
29(2):348-357.
PMID: 36652990
The SARS-CoV-2 Omicron variant has demonstrated enhanced transmissibility and escape of vaccine-derived immunity. Although first-generation vaccines remain effective against severe disease and death, robust evidence on vaccine effectiveness (VE) against...
5.
Rosa Duque J, Wang X, Leung D, Cheng S, Cohen C, Mu X, et al.
Nat Commun
. 2022 Aug;
13(1):4798.
PMID: 35970832
No abstract available.
6.
Rosa Duque J, Wang X, Leung D, Cheng S, Cohen C, Mu X, et al.
Nat Commun
. 2022 Jun;
13(1):3700.
PMID: 35764637
We present an interim analysis of a registered clinical study (NCT04800133) to establish immunobridging with various antibody and cellular immunity markers and to compare the immunogenicity and reactogenicity of 2-dose...
7.
Hachim A, Gu H, Kavian O, Mori M, Kwan M, Chan W, et al.
Nat Commun
. 2022 May;
13(1):2951.
PMID: 35618731
The antibody response magnitude and kinetics may impact clinical severity, serological diagnosis and long-term protection of COVID-19, which may play a role in why children experience lower morbidity. We therefore ...
8.
Nguyen T, Cohen C, Rowntree L, Bull M, Hachim A, Kedzierska K, et al.
Front Med (Lausanne)
. 2022 Jan;
8:793102.
PMID: 35004764
T cell responses are a key cornerstone to viral immunity to drive high-quality antibody responses, establishing memory for recall and for viral clearance. Inefficient recruitment of T cell responses plays...
9.
Wu C, Qavi A, Moyle A, Wagner N, Hachim A, Kavian N, et al.
STAR Protoc
. 2021 Oct;
2(4):100906.
PMID: 34642671
Nucleocapsid proteins are essential for SARS-CoV-2 life cycle. Here, we describe protocols to gather domain-specific insights about essential properties of nucleocapsids. These assays include dynamic light scattering to characterize oligomerization,...
10.
Valkenburg S, Cheng S, Hachim A, Peiris M, Nicholls J
Emerg Infect Dis
. 2021 Sep;
27(12):3173-3175.
PMID: 34559046
The infectivity of severe acute respiratory syndrome coronavirus 2 in deceased persons and organisms remains unclear. We studied transgenic K18 hACE2 mice to determine the kinetics of virus infectivity after...