Postmortem Stability of SARS-CoV-2 in Mouse Lung Tissue

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2021 Sep 24

PMID 34559046

Citations 1

Authors

Sophie A Valkenburg

Samuel M S Cheng

Asmaa Hachim

Malik Peiris

John Nicholls

Affiliations

Soon will be listed here.

Abstract

The infectivity of severe acute respiratory syndrome coronavirus 2 in deceased persons and organisms remains unclear. We studied transgenic K18 hACE2 mice to determine the kinetics of virus infectivity after host death. Five days after death, virus infectivity in the lung declined by >96% and RNA copies declined by 48.2%.

Citing Articles

Changes in SARS-CoV-2 viral load and titers over time in SARS-CoV-2-infected human corpses.

Nagasawa S, Hirata Y, Miyamoto S, Ozono S, Iida S, Katano H PLoS One. 2024; 19(3):e0287068.

PMID: 38536820 PMC: 10971691. DOI: 10.1371/journal.pone.0287068.

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