Ashraf N Abdalla
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Explore the profile of Ashraf N Abdalla including associated specialties, affiliations and a list of published articles.
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104
Citations
538
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Recent Articles
1.
Zulfat M, Alkhatabi H, Alreemi R, Alamri M, Khalid A, Abdalla A, et al.
J Biomol Struct Dyn
. 2024 Dec;
:1-12.
PMID: 39727343
The NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) inflammasome is a well-known and frequently cited regulator of caspase-1 activation. It plays a significant role in several pathophysiological processes and...
2.
Alghamdi A, Ahmed A, Bashir M, Abdalgadir H, Khalid A, Abdallah M, et al.
Drug Target Insights
. 2024 Oct;
18:84-93.
PMID: 39450187
Background: Edible fruits and resins provide various benefits to mankind including potential medicinal applications. This study aimed to determine the cytotoxicity, selectivity, and clonogenicity of fruits and exudates of certain...
3.
Belmehdi O, Mssillou I, Khalid A, Abdalla A, Almalki M, Alqurashi R, et al.
Chem Biodivers
. 2024 Oct;
22(2):e202401463.
PMID: 39402872
Bioactive phytochemicals act as important factors with preventive and therapeutic potential in the pathogenesis of several disorders, often related to oxidative stress. Many dietary plant secondary metabolites could lower these...
4.
Aboulaghras S, Bouyahya A, El Kadri K, Khalid A, Abdalla A, Hassani R, et al.
Microb Pathog
. 2024 Sep;
196:106919.
PMID: 39245422
A priori, early exposure to a wide range of bacteria, viruses, and parasites appears to fortify and regulate the immune system, potentially reducing the risk of autoimmune diseases. However, improving...
5.
Zulfat M, Hakami M, Hazazi A, Mahmood A, Khalid A, Alqurashi R, et al.
Heliyon
. 2024 Aug;
10(15):e34410.
PMID: 39170440
The NOD-Like Receptor Protein-3 (NLRP3) inflammasome is a key therapeutic target for the treatment of epilepsy and has been reported to regulate inflammation in several neurological diseases. In this study,...
6.
Baghdadi R, Abdalla A, Abourehab M, Tulbah A
J Taibah Univ Med Sci
. 2024 Aug;
19(4):806-815.
PMID: 39170071
Background/aim: Dasatinib (DS), a second-generation tyrosine kinase inhibitor, functions as a multi-target small-molecule drug via targeting various tyrosine kinases involved in neoplastic cell growth. DS inhibits cancer cell replication and...
7.
Identification of Novel Antileishmanial Chemotypes By High-Throughput Virtual and In Vitro Screening
Khan H, Hakami M, Alamri M, Alotaibi B, Ullah N, Khan R, et al.
Acta Parasitol
. 2024 Aug;
69(3):1439-1457.
PMID: 39150581
Background: Leishmaniasis is a deadly protozoan parasitic disease and a significant health problem in underdeveloped and developing countries. The global spread of the parasite, coupled with the emergence of drug...
8.
Shawky A, Almalki F, Alzahrani H, Abdalla A, Youssif B, Ibrahim N, et al.
Eur J Med Chem
. 2024 Aug;
277:116704.
PMID: 39121741
Since 2020, many compounds have been investigated for their potential use in the treatment of SARS-CoV-2 infection. Among these agents, a huge number of natural products and FDA-approved drugs have...
9.
Alghamdi A, Khalid A, Ahmed A, Abdalgadir H, Bashir M, Abdalla A, et al.
Discov Oncol
. 2024 Jul;
15(1):282.
PMID: 39008141
This study on Buddleja polystachya highlights its phytochemical composition, antimicrobial activity, and cytotoxic impacts. The study emphasizes the plant's potential to treat ocular diseases by identifying important compounds involved in...
10.
Aanniz T, Zeouk I, Elouafy Y, Touhtouh J, Hassani R, Hammani K, et al.
Biomed Pharmacother
. 2024 Jul;
177:117072.
PMID: 38991301
The development of natural substances derived from nature poses a significant challenge as technologies for the extraction and characterization of active principles advance. Hispolon has received a lot of attention...