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Ashok R Dinasarapu

Explore the profile of Ashok R Dinasarapu including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 146
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Recent Articles
1.
Roman K, Dinasarapu A, Cherian S, Fan X, Donsante Y, Aravind N, et al.
bioRxiv . 2024 Oct; PMID: 39415987
Striatal dysfunction is implicated in many forms of dystonia, including idiopathic, inherited and iatrogenic dystonias. The striatum is comprised largely of GABAergic spiny projection neurons (SPNs) that are defined by...
2.
Saba N, Dinasarapu A, Magliocca K, Dwivedi B, Seby S, Qin Z, et al.
PLoS One . 2024 Aug; 19(8):e0308819. PMID: 39116078
[This corrects the article DOI: 10.1371/journal.pone.0238497.].
3.
Elizaldi S, Hawes C, Verma A, Lakshmanappa Y, Dinasarapu A, Schlegel B, et al.
J Clin Invest . 2024 Mar; 134(9). PMID: 38470479
CD4+ T cells survey and maintain immune homeostasis in the brain, yet their differentiation states and functional capabilities remain unclear. Our approach, combining single-cell transcriptomic analysis, ATAC-Seq, spatial transcriptomics, and...
4.
Scorr L, Kilic-Berkmen G, Sutcliffe D, Dinasarapu A, McKay J, Bagchi P, et al.
Parkinsonism Relat Disord . 2024 Mar; 122:106036. PMID: 38462403
Background: Although there are many possible causes for cervical dystonia (CD), a specific etiology cannot be identified in most cases. Prior studies have suggested a relationship between autoimmune disease and...
5.
Kilic-Berkmen G, Kim H, Chen D, Yeo C, Dinasarapu A, Scorr L, et al.
Mov Disord . 2024 Feb; 39(4):738-745. PMID: 38310362
Background: Blepharospasm is treated with botulinum toxin, but obtaining satisfactory results is sometimes challenging. Objective: The aim is to conduct an exploratory trial of oral dipraglurant for blepharospasm. Methods: This...
6.
Roman K, Dinasarapu A, VanSchoiack A, Ross P, Kroeppler D, Jinnah H, et al.
Cell Rep . 2023 Nov; 42(11):113435. PMID: 37952158
The dorsal striatum is organized into functional territories defined by corticostriatal inputs onto both direct and indirect spiny projection neurons (SPNs), the major cell types within the striatum. In addition...
7.
Elizaldi S, Hawes C, Verma A, Dinasarapu A, Lakshmanappa Y, Schlegel B, et al.
bioRxiv . 2023 Sep; PMID: 37693567
Graphical Abstract: In Brief: Utilizing single-cell and spatial transcriptomics on adult rhesus brain, we uncover a unique CCR7+ CD4 T cell subset resembling central memory T cells (T ) within...
8.
Dinasarapu A, Sutcliffe D, Seifar F, Visser J, Jinnah H
J Neurogenet . 2022 Oct; 36(2-3):81-87. PMID: 36226509
Lesch-Nyhan disease (LND) is a neurodevelopmental disorder caused by variants in the gene, which encodes the enzyme hypoxanthine-guanine phosphoribosyl transferase (HGprt). HGprt deficiency provokes numerous metabolic changes which vary among...
9.
Hawes C, Elizaldi S, Beckman D, Diniz G, Lakshmanappa Y, Ott S, et al.
J Neuroinflammation . 2022 Oct; 19(1):250. PMID: 36203187
Background: Immunosurveillance of the central nervous system (CNS) is vital to resolve infection and injury. However, immune activation within the CNS in the setting of chronic viral infections, such as...
10.
Seifar F, Dinasarapu A, Jinnah H
Mov Disord . 2022 Sep; 37(11):2173-2183. PMID: 36056888
Numerous studies have linked Parkinson's disease (PD) with low levels of uric acid (UA). Low UA has been associated with the risk of developing PD, and its progression and severity....