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Ashish R Kurundkar

Explore the profile of Ashish R Kurundkar including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 710
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Recent Articles
1.
Rehan M, Deskin B, Kurundkar A, Yadav S, Matsunaga Y, Manges J, et al.
J Biol Chem . 2023 Jul; 299(8):105027. PMID: 37423298
Metabolism controls cellular phenotype and fate. In this report, we demonstrate that nicotinamide N-methyltransferase (NNMT), a metabolic enzyme that regulates developmental stem cell transitions and tumor progression, is highly expressed...
2.
Garg P, Middleton C, Zhang M, Paschal J, Kurundkar A, Sonani H, et al.
J Matern Fetal Neonatal Med . 2022 Oct; 35(26):10565-10576. PMID: 36261134
Objective: We sought to determine the clinical and histopathological factors linked with intestinal repair and its correlation with clinical outcomes in preterm infants following surgical necrotizing enterocolitis (NEC). Methods: A...
3.
Rehan M, Kurundkar D, Kurundkar A, Logsdon N, Smith S, Chanda D, et al.
Nat Aging . 2021 Aug; 1(2):205-217. PMID: 34386777
Aging is a risk factor for progressive fibrotic disorders involving diverse organ systems, including the lung. Idiopathic pulmonary fibrosis, an age-associated degenerative lung disorder, is characterized by persistence of apoptosis-resistant...
4.
Kulkarni T, Kurundkar A, Kim Y, De Andrade J, Luckhardt T, Thannickal V
Respir Med . 2019 Nov; 161:105821. PMID: 31765873
Introduction: Cellular senescence has been linked to the pathogenesis of idiopathic pulmonary fibrosis (IPF). CCN1 is a matricellular protein that has been shown to induce cellular senescence and contribute to...
5.
Kurundkar D, Kurundkar A, Bone N, Becker Jr E, Liu W, Chacko B, et al.
JCI Insight . 2019 Jan; 4(1). PMID: 30626741
Acute lung injury (ALI) is characterized by exuberant proinflammatory responses and mitochondrial dysfunction. However, the link between mitochondrial dysfunction and inflammation in ALI is not well understood. In this report,...
6.
Ding Q, Subramanian I, Luckhardt T, Che P, Waghray M, Zhao X, et al.
Am J Physiol Lung Cell Mol Physiol . 2017 Apr; 312(6):L926-L935. PMID: 28360109
Alveolar epithelial cell (AEC) injury and apoptosis are prominent pathological features of idiopathic pulmonary fibrosis (IPF). There is evidence of AEC plasticity in lung injury repair response and in IPF....
7.
Kurundkar A, Kurundkar D, Rangarajan S, Locy M, Zhou Y, Liu R, et al.
FASEB J . 2016 Feb; 30(6):2135-50. PMID: 26884454
Matricellular proteins mediate pleiotropic effects during tissue injury and repair. CCN1 is a matricellular protein that has been implicated in angiogenesis, inflammation, and wound repair. In this study, we identified...
8.
Ma I, McConaghy S, Namachivayam K, Halloran B, Kurundkar A, MohanKumar K, et al.
Pediatr Res . 2015 Jan; 77(4):500-5. PMID: 25588190
Background: Vascular endothelial growth factor (VEGF), a well-characterized regulator of angiogenesis, has been mechanistically implicated in retinal neovascularization and in the pathogenesis of retinopathy of prematurity. However, the ontogeny of...
9.
MohanKumar K, Killingsworth C, McIlwain R, Timpa J, Jagadeeswaran R, Namachivayam K, et al.
Lab Invest . 2013 Dec; 94(2):150-60. PMID: 24365747
Neonates and young infants exposed to extracorporeal circulation during extracorporeal membrane oxygenation (ECMO) and cardiopulmonary bypass are at risk of developing a systemic inflammatory response syndrome with multi-organ dysfunction. We...
10.
MohanKumar K, Kaza N, Jagadeeswaran R, Garzon S, Bansal A, Kurundkar A, et al.
Am J Physiol Gastrointest Liver Physiol . 2012 Apr; 303(1):G93-102. PMID: 22538401
Necrotizing enterocolitis (NEC) is an inflammatory bowel necrosis of premature infants. In tissue samples of NEC, we identified numerous macrophages and a few neutrophils but not many lymphocytes. We hypothesized...