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Asa Nordling

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Citations 486
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11.
Neve E, Kofeler H, Hendriks D, Nordling A, Gogvadze V, Mkrtchian S, et al.
PLoS One . 2015 Sep; 10(9):e0138487. PMID: 26378779
Recently two novel enzymes were identified in the outer mitochondrial membrane, mARC1 and mARC2. These molybdenum containing enzymes can reduce a variety of N-hydroxylated compounds, such as N-hydroxy-guanidines and sulfohydroxamic...
12.
Choong E, Loryan I, Lindqvist M, Nordling A, El Bouazzaoui S, van Schaik R, et al.
Basic Clin Pharmacol Toxicol . 2013 Mar; 113(2):126-31. PMID: 23527701
Women recover faster from propofol anaesthesia and have been described to have a higher incidence of awareness during surgery, compared to men - an effect that may be inherent in...
13.
Neve E, Nordling A, Andersson T, Hellman U, Diczfalusy U, Johansson I, et al.
J Biol Chem . 2011 Dec; 287(9):6307-17. PMID: 22203676
Reduction of hydroxylamines and amidoximes is important for drug activation and detoxification of aromatic and heterocyclic amines. Such a reductase system was previously found to be of high activity in...
14.
Andersson S, Hofmann Y, Nordling A, Li X, Nivelius S, Andersson T, et al.
Drug Metab Dispos . 2005 Jan; 33(4):570-8. PMID: 15640373
The enzymic basis for intracellular reduction of N-hydroxylated amidines to their corresponding amidines, and hydroxylamines to their corresponding amines, is unknown. The hydroxylated amidines can be used as prodrug moieties,...