Arun K Haldar
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Explore the profile of Arun K Haldar including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
723
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0
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Recent Articles
1.
Finethy R, Dockterman J, Kutsch M, Orench-Rivera N, Wallace G, Piro A, et al.
EMBO Rep
. 2020 Oct;
21(11):e50830.
PMID: 33124745
Inflammation associated with gram-negative bacterial infections is often instigated by the bacterial cell wall component lipopolysaccharide (LPS). LPS-induced inflammation and resulting life-threatening sepsis are mediated by the two distinct LPS...
2.
Finethy R, Luoma S, Orench-Rivera N, Feeley E, Haldar A, Yamamoto M, et al.
mBio
. 2017 Oct;
8(5).
PMID: 28974614
The Gram-negative bacterial cell wall component lipopolysaccharide (LPS) is recognized by the noncanonical inflammasome protein caspase-11 in the cytosol of infected host cells and thereby prompts an inflammatory immune response...
3.
Haldar A, Piro A, Finethy R, Espenschied S, Brown H, Giebel A, et al.
mBio
. 2016 Dec;
7(6).
PMID: 27965446
Importance: Chlamydia trachomatis is the leading cause of sexually transmitted bacterial infections and responsible for significant morbidity, including pelvic inflammatory disease, infertility, and ectopic pregnancies in women. As an obligate...
4.
Coers J, Haldar A
Commun Integr Biol
. 2016 Apr;
8(6):e1115163.
PMID: 27066178
Many intracellular bacterial and protozoan pathogens reside within host cell vacuoles customized by the microbial invaders to fit their needs. Within such pathogen-containing vacuoles (PVs) microbes procure nutrients and simultaneously...
5.
Haldar A, Foltz C, Finethy R, Piro A, Feeley E, Pilla-Moffett D, et al.
Proc Natl Acad Sci U S A
. 2015 Sep;
112(41):E5628-37.
PMID: 26417105
Many microbes create and maintain pathogen-containing vacuoles (PVs) as an intracellular niche permissive for microbial growth and survival. The destruction of PVs by IFNγ-inducible guanylate binding protein (GBP) and immunity-related...
6.
Finethy R, Jorgensen I, Haldar A, de Zoete M, Strowig T, Flavell R, et al.
Infect Immun
. 2015 Sep;
83(12):4740-9.
PMID: 26416908
Interferon (IFN)-inducible guanylate binding proteins (GBPs) mediate cell-autonomous host resistance to bacterial pathogens and promote inflammasome activation. The prevailing model postulates that these two GBP-controlled activities are directly linked through...
7.
Pilla D, Hagar J, Haldar A, Mason A, Degrandi D, Pfeffer K, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(16):6046-51.
PMID: 24715728
IFN receptor signaling induces cell-autonomous immunity to infections with intracellular bacterial pathogens. Here, we demonstrate that IFN-inducible guanylate binding protein (Gbp) proteins stimulate caspase-11-dependent, cell-autonomous immunity in response to cytoplasmic...
8.
Haldar A, Piro A, Pilla D, Yamamoto M, Coers J
PLoS One
. 2014 Jan;
9(1):e86684.
PMID: 24466199
Cell-autonomous immunity to the bacterial pathogen Chlamydia trachomatis and the protozoan pathogen Toxoplasma gondii is controlled by two families of Interferon (IFN)-inducible GTPases: Immunity Related GTPases (IRGs) and Guanylate binding...
9.
Haldar A, Saka H, Piro A, Dunn J, Henry S, Taylor G, et al.
PLoS Pathog
. 2013 Jun;
9(6):e1003414.
PMID: 23785284
Interferon-inducible GTPases of the Immunity Related GTPase (IRG) and Guanylate Binding Protein (GBP) families provide resistance to intracellular pathogenic microbes. IRGs and GBPs stably associate with pathogen-containing vacuoles (PVs) and...