Arturo Zychlinsky
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Explore the profile of Arturo Zychlinsky including associated specialties, affiliations and a list of published articles.
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82
Citations
17521
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Recent Articles
11.
Cossarizza A, Chang H, Radbruch A, Acs A, Adam D, Adam-Klages S, et al.
Eur J Immunol
. 2019 Oct;
49(10):1457-1973.
PMID: 31633216
These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry...
12.
Knackstedt S, Georgiadou A, Apel F, Abu-Abed U, Moxon C, Cunnington A, et al.
Sci Immunol
. 2019 Oct;
4(40).
PMID: 31628160
Neutrophils are essential innate immune cells that extrude chromatin in the form of neutrophil extracellular traps (NETs) when they die. This form of cell death has potent immunostimulatory activity. We...
13.
Kenny E, Raupach B, Abu Abed U, Brinkmann V, Zychlinsky A
Eur J Immunol
. 2019 Feb;
49(4):590-599.
PMID: 30758851
Systemic lupus erythematosus (SLE) is an autoimmune disease that has high morbidity and can result in multi-organ damage. SLE is characterized by dysregulated activation of T- and B-lymphocytes and the...
14.
Ley K, Hoffman H, Kubes P, Cassatella M, Zychlinsky A, Hedrick C, et al.
Sci Immunol
. 2018 Dec;
3(30).
PMID: 30530726
Neutrophils are the first line of defense against bacteria and fungi and help combat parasites and viruses. They are necessary for mammalian life, and their failure to recover after myeloablation...
15.
Sollberger G, Choidas A, Burn G, Habenberger P, Di Lucrezia R, Kordes S, et al.
Sci Immunol
. 2018 Aug;
3(26).
PMID: 30143555
The death of a cell is an inevitable part of its biology. During homeostasis, most cells die through apoptosis. If homeostasis is disturbed, cell death can switch to proinflammatory forms...
16.
Apel F, Zychlinsky A, Kenny E
Nat Rev Rheumatol
. 2018 Jun;
14(8):467-475.
PMID: 29930301
Rheumatic diseases are a collection of disorders defined by the presence of inflammation and destruction of joints and internal organs. A common feature of these diseases is the presence of...
17.
Sollberger G, Tilley D, Zychlinsky A
Dev Cell
. 2018 Mar;
44(5):542-553.
PMID: 29533770
Neutrophils are essential to the homeostatic mission of safeguarding host tissues, responding rapidly and diversely to breaches of the host's barriers to infection, and returning tissues to a sterile state....
18.
Virreira Winter S, Zychlinsky A
J Biol Chem
. 2018 Feb;
293(13):4893-4900.
PMID: 29414783
Inflammasomes are cytosolic complexes that mature and secrete the inflammatory cytokines interleukin 1β (IL-1β) and IL-18 and induce pyroptosis. The NLRP3 (NACHT, LRR, and PYD domains-containing protein 3) inflammasome detects...
19.
Deigendesch N, Zychlinsky A, Meissner F
J Immunol
. 2018 Jan;
200(5):1607-1617.
PMID: 29358279
Inflammasomes are multimeric protein complexes that are activated through a NOD-like receptor and regulate the proteolytic activation of caspase-1 and cytokines, like IL-1β. The NLRP3 inflammasome is implicated in many...
20.
Amulic B, Knackstedt S, Abu Abed U, Deigendesch N, Harbort C, Caffrey B, et al.
Dev Cell
. 2017 Nov;
43(4):449-462.e5.
PMID: 29103955
Neutrophils are essential for immune defense and can respond to infection by releasing chromatin in the form of neutrophil extracellular traps (NETs). Here we show that NETs are induced by...