Artika P Nath
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Explore the profile of Artika P Nath including associated specialties, affiliations and a list of published articles.
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15
Citations
462
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Recent Articles
1.
Bond S, King E, Walker S, Yang C, Liu Y, Liu K, et al.
Nat Commun
. 2025 Mar;
16(1):2338.
PMID: 40057508
During mitochondrial damage, information is relayed between the mitochondria and nucleus to coordinate precise responses to preserve cellular health. One such pathway is the mitochondrial integrated stress response (mtISR), which...
2.
Tokolyi A, Persyn E, Nath A, Burnham K, Marten J, Vanderstichele T, et al.
Nat Genet
. 2025 Mar;
57(3):616-625.
PMID: 40038547
The biological mechanisms through which most nonprotein-coding genetic variants affect disease risk are unknown. To investigate gene-regulatory mechanisms, we mapped blood gene expression and splicing quantitative trait loci (QTLs) through...
3.
Hai H, Nhat L, Tram T, Vinh D, Nath A, Donovan J, et al.
Elife
. 2024 Oct;
13.
PMID: 39475467
Mortality and morbidity from tuberculous meningitis (TBM) are common, primarily due to inflammatory response to infection, yet the underlying mechanisms remain poorly understood. We aimed to uncover genes and pathways...
4.
Vanderstichele T, Burnham K, de Klein N, Tardaguila M, Howell B, Walter K, et al.
Am J Hum Genet
. 2024 Jul;
111(8):1524-1543.
PMID: 39053458
Gene misexpression is the aberrant transcription of a gene in a context where it is usually inactive. Despite its known pathological consequences in specific rare diseases, we have a limited...
5.
Kanki M, Nath A, Xiang R, Yiallourou S, Fuller P, Cole T, et al.
Nat Commun
. 2023 Nov;
14(1):7096.
PMID: 37925459
Disrupted circadian rhythms have been linked to an increased risk of hypertension and cardiovascular disease. However, many studies show inconsistent findings and are not sufficiently powered for targeted subgroup analyses....
6.
Xu Y, Ritchie S, Liang Y, Timmers P, Pietzner M, Lannelongue L, et al.
Nature
. 2023 Mar;
616(7955):123-131.
PMID: 36991119
The use of omic modalities to dissect the molecular underpinnings of common diseases and traits is becoming increasingly common. But multi-omic traits can be genetically predicted, which enables highly cost-effective...
7.
Foguet C, Xu Y, Ritchie S, Lambert S, Persyn E, Nath A, et al.
Nat Commun
. 2022 Nov;
13(1):7356.
PMID: 36446790
Understanding how genetic variants influence disease risk and complex traits (variant-to-function) is one of the major challenges in human genetics. Here we present a model-driven framework to leverage human genome-scale...
8.
Bond S, King E, Henstridge D, Tran A, Moody S, Yang C, et al.
Nat Commun
. 2021 Jan;
12(1):74.
PMID: 33397965
The effective storage of lipids in white adipose tissue (WAT) critically impacts whole body energy homeostasis. Many genes have been implicated in WAT lipid metabolism, including tripartite motif containing 28...
9.
Huang Q, Tang H, Teo S, Mok D, Ritchie S, Nath A, et al.
Nat Commun
. 2020 Jul;
11(1):3761.
PMID: 32724101
Chronic immune-mediated diseases of adulthood often originate in early childhood. To investigate genetic associations between neonatal immunity and disease, we map expression quantitative trait loci (eQTLs) in resting myeloid cells...
10.
Nath A, Ritchie S, Grinberg N, Tang H, Huang Q, Teo S, et al.
Am J Hum Genet
. 2019 Nov;
105(6):1076-1090.
PMID: 31679650
Cytokines are essential regulatory components of the immune system, and their aberrant levels have been linked to many disease states. Despite increasing evidence that cytokines operate in concert, many of...