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Arthur C Watterson

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Articles 17
Citations 91
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Recent Articles
1.
Kumar A, Khan A, Malhotra S, Mosurkal R, Dhawan A, Pandey M, et al.
Chem Soc Rev . 2016 Oct; 45(24):6855-6887. PMID: 27785498
Enzymes, being remarkable catalysts, are capable of accepting a wide range of complex molecules as substrates and catalyze a variety of reactions with a high degree of chemo-, stereo- and...
2.
Khan A, Sharma S, Kumar A, Watterson A, Kumar J, Parmar V
ChemSusChem . 2014 Jan; 7(2):379-90. PMID: 24449474
The adverse impact of chemical and biochemical waste on the environment and human health poses a serious challenge in today's World. The best way to address these challenges is to...
3.
Pandey M, Kumar S, Thimmulappa R, Parmar V, Biswal S, Watterson A
Eur J Pharm Sci . 2011 Mar; 43(1-2):16-24. PMID: 21426935
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a central transcription factor that regulates the anti-oxidant defense system and is considered as a modifier for several inflammatory diseases. Thus, activation of...
4.
Pandey M, Balwani S, Sharma P, Parmar V, Ghosh B, Watterson A
Eur J Pharm Sci . 2009 Dec; 39(1-3):134-40. PMID: 19948217
Aberrant interaction between the leukocyte and the endothelial cell (EC) resulting from the deregulated expression of cell adhesion molecules (CAMs) on the endothelium results in uncontrolled inflammation leading to various...
5.
Kumar A, Singh B, Sharma N, Gyanda K, Jain S, Tyagi Y, et al.
Eur J Med Chem . 2006 Dec; 42(4):447-55. PMID: 17182154
The earlier work carried out in our laboratory led to the identification of a novel rat liver microsomal enzyme termed as acetoxy drug: protein transacetylase (TAase), catalyzing the transfer of...
6.
Chhillar A, Arya P, Mukherjee C, Kumar P, Yadav Y, Sharma A, et al.
Bioorg Med Chem . 2005 Oct; 14(4):973-81. PMID: 16214352
Ten 4-aryl-1,4-dihydropyridine and three 4-aryl-1,2,3,4-tetrahydropyrimidin-2-one derivatives have been synthesized and examined for their activity against pathogenic strains of Aspergillus fumigatus and Candida albicans. Although none of the three compounds belonging...
7.
Shea T, Ortiz D, Nicolosi R, Kumar R, Watterson A
J Alzheimers Dis . 2005 Sep; 7(4):297-301. PMID: 16131731
Oxidative stress is an early hallmark of affected neurons in Alzheimer's disease (AD). The antioxidant vitamin E provided limited neuroprotection in AD, which may have derived from its lipophilic nature...
8.
Kumar A, Singh B, Tyagi R, Jain S, Sharma S, Prasad A, et al.
Bioorg Med Chem . 2005 May; 13(13):4300-5. PMID: 15878663
Our earlier observations led to the identification of a microsomal enzyme termed as acetoxy drug: protein transacetylase (TAase) catalyzing the transfer of acetyl groups from acetylated polyphenols to the receptor...
9.
Sharma S, Kumar R, Kumar S, Mosurkal R, Parmar V, Samuelson L, et al.
Chem Commun (Camb) . 2004 Nov; (23):2689-91. PMID: 15568069
We have evaluated the influence of aromatic and hydrophobic interactions on the strength and selectivity of encapsulation using polymeric nanospheres.
10.
Kumar R, Chen M, Parmar V, Samuelson L, Kumar J, Nicolosi R, et al.
J Am Chem Soc . 2004 Aug; 126(34):10640-4. PMID: 15327322
A chemoenzymatic approach has been developed to synthesize poly(ethylene glycol)-based amphiphilic copolymers under mild reaction conditions that self-assemble in aqueous media to form polymeric nanomicelles in the range of 20-50...