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Aron Szepesi

Explore the profile of Aron Szepesi including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 153
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Recent Articles
1.
Judak L, Dobos G, Ocsai K, Bathory E, Szebik H, Tarjan B, et al.
Nat Methods . 2024 Dec; 22(2):386-398. PMID: 39668210
Due to technical roadblocks, it is unclear how visual circuits represent multiple features or how behaviorally relevant representations are selected for long-term memory. Here we developed Moculus, a head-mounted virtual...
2.
Mathe D, Szalay G, Cseri L, Kis Z, Palyi B, Foldes G, et al.
Cell Mol Biol Lett . 2024 Jul; 29(1):105. PMID: 39030477
Background: The organism-wide effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral infection are well studied, but little is known about the dynamics of how the infection spreads in...
3.
Vajda F, Szepesi A, Erdei Z, Szabo E, Varady G, Kiss D, et al.
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38674102
Mesenchymal stem cells (MSCs) are an integral part of the tumor microenvironment (TME); however, their role is somewhat controversial: conflicting reports suggest that, depending on the stage of tumor development,...
4.
Judak L, Chiovini B, Juhasz G, Palfi D, Mezriczky Z, Szadai Z, et al.
Nat Commun . 2022 Nov; 13(1):6715. PMID: 36344570
Neuronal plasticity has been shown to be causally linked to coincidence detection through dendritic spikes (dSpikes). We demonstrate the existence of SPW-R-associated, branch-specific, local dSpikes and their computational role in...
5.
Vajda F, Szepesi A, Varady G, Sessler J, Kiss D, Erdei Z, et al.
Cells . 2022 Oct; 11(19). PMID: 36230904
Mesenchymal stem cells (MSCs) or fibroblasts are one of the most abundant cell types in the tumor microenvironment (TME) exerting various anti- and pro-apoptotic effects during tumorigenesis, invasion, and drug...
6.
Toth S, Szepesi A, Tran-Nguyen V, Sarkadi B, Nemet K, Falson P, et al.
Molecules . 2020 Feb; 25(3). PMID: 32050702
The resistance of tumors against anticancer drugs is a major impediment for chemotherapy. Tumors often develop multidrug resistance as a result of the cellular efflux of chemotherapeutic agents by ABC...
7.
Windt T, Toth S, Patik I, Sessler J, Kucsma N, Szepesi A, et al.
Arch Toxicol . 2019 Mar; 93(4):953-964. PMID: 30863990
Membrane transporters play an important role in the absorption, distribution, metabolism and excretion of drugs. The cellular accumulation of many drugs is the result of the net function of efflux...
8.
Patik I, Szekely V, Nemet O, Szepesi A, Kucsma N, Varady G, et al.
Sci Rep . 2018 Feb; 8(1):2630. PMID: 29422623
Organic Anion-Transporting Polypeptides are multispecific membrane proteins that regulate the passage of crucial endobiotics and drugs across pharmacological barriers. OATP1B1 and OATP1B3 have been described to play a major role...
9.
Szepesi A, Matula Z, Szigeti A, Varady G, Szalma J, Szabo G, et al.
Stem Cells Int . 2016 Dec; 2016:3595941. PMID: 27999599
Bone tissue regeneration is a major, worldwide medical need, and several strategies have been developed to support the regeneration of extensive bone defects, including stem cell based bone grafts. In...
10.
Nerada Z, Hegyi Z, Szepesi A, Toth S, Hegedus C, Varady G, et al.
Cytometry A . 2016 Sep; 89(9):826-34. PMID: 27602881
ABC multidrug transporters are key players in cancer multidrug resistance and in determining the ADME-Tox properties of drugs and xenobiotics. The most sensitive and specific detection of these transporters is...