Arjun N Sasikumar
Overview
Explore the profile of Arjun N Sasikumar including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
180
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Recent Articles
1.
Sasikumar A, Killilea D, Kennedy B, Brem R
Exp Gerontol
. 2019 Feb;
120:101-106.
PMID: 30742903
Lysosome function is compromised during aging and in many disease states. Interventions that promote lysosomal activity and acidification are thus of prime interest as treatments for longevity and health. Intracellular...
2.
Sasikumar A, Kinzy T
J Biol Chem
. 2014 Jan;
289(8):4853-60.
PMID: 24379402
Translation elongation is mediated by ribosomes and multiple soluble factors, many of which are conserved across bacteria and eukaryotes. During elongation, eukaryotic elongation factor 1A (eEF1A; EF-Tu in bacteria) delivers...
3.
Sasikumar A, Perez W, Kinzy T
Wiley Interdiscip Rev RNA
. 2012 May;
3(4):543-55.
PMID: 22555874
The vast majority of proteins are believed to have one specific function. Throughout the course of evolution, however, some proteins have acquired additional functions to meet the demands of a...
4.
Esposito A, Mateyak M, He D, Lewis M, Sasikumar A, Hutton J, et al.
J Vis Exp
. 2010 Jun;
(40).
PMID: 20567211
Protein synthesis is a complex cellular process that is regulated at many levels. For example, global translation can be inhibited at the initiation phase or the elongation phase by a...