Ariel A Bazzini
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Explore the profile of Ariel A Bazzini including associated specialties, affiliations and a list of published articles.
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30
Citations
1905
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Recent Articles
1.
Kushawah G, Baia Amaral D, Hassan H, Gogol M, Nowotarski S, Bazzini A
bioRxiv
. 2024 Nov;
PMID: 39574587
The maternal-to-zygotic transition shifts regulatory control from maternal to zygotic messenger RNAs (mRNA) through maternal mRNA degradation. While temporal aspects of maternal mRNA decay are known, spatial mechanisms remain underexplored....
2.
DeVore M, Bazzini A
G3 (Bethesda)
. 2024 Oct;
PMID: 39446991
The ribosome plays a crucial role in translating mRNA into protein; however, the genetic code extends beyond merely specifying amino acids. Upon translation, codons, the three-nucleotide sequences interpreted by ribosomes,...
3.
Deutsch E, Kok L, Mudge J, Ruiz-Orera J, Fierro-Monti I, Sun Z, et al.
bioRxiv
. 2024 Sep;
PMID: 39314370
A major scientific drive is to characterize the protein-coding genome as it provides the primary basis for the study of human health. But the fundamental question remains: what has been...
4.
da Silva Pescador G, Baia Amaral D, Varberg J, Zhang Y, Hao Y, Florens L, et al.
Cell Rep
. 2024 Sep;
43(10):114769.
PMID: 39302832
The maternal-to-zygotic transition is crucial in embryonic development, marked by the degradation of maternally provided mRNAs and initiation of zygotic gene expression. However, the changes occurring at the protein level...
5.
Castellano L, McNamara R, Pallares H, Gamarnik A, Alvarez D, Bazzini A
Mol Syst Biol
. 2024 Jul;
20(10):1085-1108.
PMID: 39039212
Codon optimality refers to the effect that codon composition has on messenger RNA (mRNA) stability and translation level and implies that synonymous codons are not silent from a regulatory point...
6.
Pallares H, Gonzalez Lopez Ledesma M, Oviedo-Rouco S, Castellano L, Costa Navarro G, Fernandez-Alvarez A, et al.
Nucleic Acids Res
. 2024 Jun;
52(18):11128-11147.
PMID: 38917323
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that causes severe outbreaks in human populations. ZIKV infection leads to the accumulation of small non-coding viral RNAs (known as sfRNAs) that...
7.
Hernandez-Huertas L, Moreno-Sanchez I, Crespo-Cuadrado J, Vargas-Baco A, da Silva Pescador G, Santos-Pereira J, et al.
bioRxiv
. 2024 Jun;
PMID: 38826327
The Maternal-to-Zygotic transition (MZT) is a reprograming process encompassing zygotic genome activation (ZGA) and the clearance of maternally-provided mRNAs. While some factors regulating MZT have been identified, there are thousands...
8.
Baia Amaral D, Egidy R, Perera A, Bazzini A
Genome Biol
. 2024 Mar;
25(1):74.
PMID: 38504288
Background: Early embryonic developmental programs are guided by the coordinated interplay between maternally inherited and zygotically manufactured RNAs and proteins. Although these processes happen concomitantly and affecting gene function during...
9.
Wu Q, Bazzini A
Annu Rev Biochem
. 2023 Mar;
92:227-245.
PMID: 37001134
Messenger RNA (mRNA) stability and translational efficiency are two crucial aspects of the post-transcriptional process that profoundly impact protein production in a cell. While it is widely known that ribosomes...
10.
Mudge J, Ruiz-Orera J, Prensner J, Brunet M, Calvet F, Jungreis I, et al.
Nat Biotechnol
. 2022 Jul;
40(7):994-999.
PMID: 35831657
No abstract available.