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Antonis C Antoniou

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Articles 279
Citations 15945
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Recent Articles
1.
Ip S, Harrison H, Usher-Smith J, Barclay M, Tyrer J, Dennis J, et al.
BMJ Oncol . 2025 Mar; 4(1):e000336. PMID: 40046831
Objectives: To quantify the contributions of polygenic scores, primary care records (presenting symptoms, medical history and common blood tests) and lifestyle factors, for short-term risk prediction of colorectal cancer (CRC)...
2.
Hassan H, Rahman T, Bacon A, Knott C, Allen I, Huntley C, et al.
BMJ Oncol . 2025 Mar; 4(1):e000574. PMID: 40046828
Objectives: To investigate the association between bilateral salpingo-oophorectomy (BSO) and long-term health outcomes in women with a personal history of breast cancer. Methods And Analysis: We used data on women...
3.
Hoppe R, Winter S, Lo W, Michailidou K, Bolla M, Keeman R, et al.
NPJ Breast Cancer . 2025 Feb; 11(1):18. PMID: 39971965
The role of germline genetics in adjuvant aromatase inhibitor (AI) treatment efficacy in ER-positive breast cancer is poorly understood. We employed a two-stage candidate gene approach to examine associations between...
4.
Mavaddat N, Ficorella L, Carver T, Lee A, Cunningham A, Lush M, et al.
Cancer Epidemiol Biomarkers Prev . 2025 Jan; 34(1):205. PMID: 39780621
No abstract available.
5.
Mulder C, Yang X, Jee Y, Scott C, Gao C, Cao Y, et al.
Res Sq . 2025 Jan; PMID: 39764121
Introduction: Incorporation of mammographic density to breast cancer risk models could improve risk stratification to tailor screening and prevention strategies according to risk. Robust evaluation of the value of adding...
6.
Yiangou K, Mavaddat N, Dennis J, Zanti M, Wang Q, Bolla M, et al.
Breast Cancer Res . 2024 Dec; 26(1):189. PMID: 39734228
Background: The 313-variant polygenic risk score (PRS) provides a promising tool for clinical breast cancer risk prediction. However, evaluation of the PRS across different European populations which could influence risk...
7.
Petitjean C, Wilcox N, Ficorella L, Dennis J, Tyrer J, Lush M, et al.
J Natl Cancer Inst . 2024 Dec; PMID: 39666943
Background: The BOADICEA model predicts breast cancer risk using cancer family history, epidemiological and genetic data. We evaluated its validity in a large prospective cohort. Methods: We assessed model calibration,...
8.
Li S, Madanat-Harjuoja L, Leslie G, Barnes D, Bolla M, Dennis J, et al.
J Natl Cancer Inst . 2024 Nov; PMID: 39585318
Background: Whether carriers of BRCA1 or BRCA2 (BRCA1/2) pathogenic variants (PVs) have increased risks of childhood, adolescent, and young adult (CAYA) cancers is controversial. We aimed to evaluate this risk...
9.
Manchanda R, Evans D, Antoniou A, Brentnall A
BJC Rep . 2024 Nov; 2(1):24. PMID: 39516688
No abstract available.
10.
Usher-Smith J, Tooth G, Follows A, Badran A, Youngs A, Forman A, et al.
BJC Rep . 2024 Nov; 2(1):2. PMID: 39516250
Background: The National Institute for Health and Care Excellence (NICE) recommends that women in England at above-population risk be offered additional breast screening and, depending on the level of risk,...