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Antoine G Almonte

Explore the profile of Antoine G Almonte including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Bach E, Ewin S, Heaney C, Carlson H, Ortelli O, Almonte A, et al.
Eur J Neurosci . 2023 Feb; 57(8):1241-1259. PMID: 36840503
Alcohol use disorder (AUD) and anxiety/stressor disorders frequently co-occur and this dual diagnosis represents a major health and economic problem worldwide. The basolateral amygdala (BLA) is a key brain region...
2.
Ewin S, Morgan J, Niere F, McMullen N, Barth S, Almonte A, et al.
Neuroscience . 2018 Nov; 398:144-157. PMID: 30481568
Many studies have implicated hippocampal dysregulation in the pathophysiology of alcohol use disorder (AUD). However, over the past twenty years, a growing body of evidence has revealed distinct functional roles...
3.
Almonte A, Ewin S, Mauterer M, Morgan J, Carter E, Weiner J
Sci Rep . 2017 Sep; 7(1):12300. PMID: 28951619
It has long been appreciated that adolescence represents a uniquely vulnerable period when chronic exposure to stressors can precipitate the onset of a broad spectrum of psychiatric disorders and addiction...
4.
Adamah-Biassi E, Almonte A, Blagovechtchenski E, Grinevich V, Weiner J, Bonin K, et al.
J Neurosci Methods . 2015 Aug; 256:56-62. PMID: 26310181
Background: Adenosine serves many functions within the CNS, including inhibitory and excitatory control of neurotransmission. The understanding of adenosine dynamics in the brain is of fundamental importance. The goal of...
5.
Clement J, Aceti M, Creson T, Ozkan E, Shi Y, Reish N, et al.
Cell . 2012 Nov; 151(4):709-723. PMID: 23141534
Mutations that cause intellectual disability (ID) and autism spectrum disorder (ASD) are commonly found in genes that encode for synaptic proteins. However, it remains unclear how mutations that disrupt synapse...
6.
Almonte A, Qadri L, Sultan F, Watson J, Mount D, Rumbaugh G, et al.
J Neurochem . 2012 Nov; 124(1):109-22. PMID: 23113835
Protease-activated receptor-1 (PAR1) is an unusual G-protein coupled receptor (GPCR) that is activated through proteolytic cleavage by extracellular serine proteases. Although previous work has shown that inhibiting PAR1 activation is...
7.
Almonte A, Sweatt J
Brain Res . 2011 Jul; 1407:107-22. PMID: 21782155
Serine proteases, serine protease inhibitors, and protease-activated receptors have been intensively investigated in the periphery and their roles in a wide range of processes-coagulation, inflammation, and digestion, for example-have been...
8.
Kang S, Han K, Ku B, Lee Y, Hong J, Shin H, et al.
Cancer Res . 2010 Jan; 70(3):1173-83. PMID: 20103623
Calcium signaling is important in many signaling processes in cancer cell proliferation and motility including in deadly glioblastomas of the brain that aggressively invade neighboring tissue. We hypothesized that disturbing...
9.
Almonte A, Hamill C, Chhatwal J, Wingo T, Barber J, Lyuboslavsky P, et al.
Neurobiol Learn Mem . 2007 Jun; 88(3):295-304. PMID: 17544303
The roles of serine proteases and protease activated receptors have been extensively studied in coagulation, wound healing, inflammation, and neurodegeneration. More recently, serine proteases have been suggested to influence synaptic...
10.
Borges K, Gearing M, McDermott D, Smith A, Almonte A, Wainer B, et al.
Exp Neurol . 2003 Jun; 182(1):21-34. PMID: 12821374
The rodent pilocarpine model of epilepsy exhibits hippocampal sclerosis and spontaneous seizures and thus resembles human temporal lobe epilepsy. Use of the many available mouse mutants to study this epilepsy...