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Anthony M C Brown

Explore the profile of Anthony M C Brown including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 1749
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Recent Articles
1.
You Z, Saims D, Chen S, Zhang Z, Guttridge D, Guan K, et al.
J Cell Biol . 2021 Apr; 220(5). PMID: 33830173
No abstract available.
2.
Losa M, Risolino M, Li B, Hart J, Quintana L, Grishina I, et al.
Development . 2018 Feb; 145(5). PMID: 29437830
Human cleft lip with or without cleft palate (CL/P) is a common craniofacial abnormality caused by impaired fusion of the facial prominences. We have previously reported that, in the mouse...
3.
Zhang L, Adileh M, Martin M, Klingler S, White J, Ma X, et al.
Cell Signal . 2016 Nov; 29:41-51. PMID: 27511963
Recent evidence suggests that mammary cells expressing R-spondin receptor and Wnt pathway regulator Lgr5, regarded as a stem cell marker in multiple tissues, might represent mammary stem cells (MaSCs). Whether...
4.
Bussche L, Rauner G, Antonyak M, Syracuse B, McDowell M, Brown A, et al.
J Biol Chem . 2016 Oct; 291(47):24390-24405. PMID: 27733685
Signaling mechanisms that regulate mammary stem/progenitor cell (MaSC) self-renewal are essential for developmental changes that occur in the mammary gland during pregnancy, lactation, and involution. We observed that equine MaSCs...
5.
Dass R, Sarshad A, Carson B, Feenstra J, Kaur A, Obrdlik A, et al.
PLoS Genet . 2016 Aug; 12(8):e1006217. PMID: 27500936
Ribosome biogenesis is essential for cell growth and proliferation and is commonly elevated in cancer. Accordingly, numerous oncogene and tumor suppressor signaling pathways target rRNA synthesis. In breast cancer, non-canonical...
6.
Many A, Brown A
PLoS One . 2014 Jul; 9(7):e101800. PMID: 25019931
The characterization of mammary stem cells, and signals that regulate their behavior, is of central importance in understanding developmental changes in the mammary gland and possibly for targeting stem-like cells...
7.
Stadler S, Vincent C, Fedorov V, Patsialou A, Cherrington B, Wakshlag J, et al.
Proc Natl Acad Sci U S A . 2013 Jul; 110(29):11851-6. PMID: 23818587
Peptidylarginine deiminase 4 (PAD4) is a Ca(2+)-dependent enzyme that converts arginine and methylarginine residues to citrulline, with histone proteins being among its best-described substrates to date. However, the biological function...
8.
Gray J, Kholmanskikh S, Castaldo B, Hansler A, Chung H, Klotz B, et al.
Hum Mol Genet . 2013 Jun; 22(21):4267-81. PMID: 23773994
Low-density lipoprotein receptor related protein 6 (Lrp6) mutational effects on neurulation were examined using gain (Crooked tail, Lrp6(Cd)) and loss (Lrp6(-)) of function mouse lines. Two features often associated with...
9.
Greer Y, Fields A, Brown A, Rubin J
J Biol Chem . 2013 Feb; 288(13):9438-46. PMID: 23396968
Previously we reported that Wnt3a-dependent neurite outgrowth in Ewing sarcoma family tumor cell lines was mediated by Frizzled3, Dishevelled (Dvl), and c-Jun N-terminal kinase (Endo, Y., Beauchamp, E., Woods, D.,...
10.
Gonzalez-Sancho J, Greer Y, Abrahams C, Takigawa Y, Baljinnyam B, Lee K, et al.
J Biol Chem . 2013 Feb; 288(13):9428-37. PMID: 23396967
Dishevelled (Dvl) proteins are intracellular effectors of Wnt signaling that have essential roles in both canonical and noncanonical Wnt pathways. It has long been known that Wnts stimulate Dvl phosphorylation,...