Anthony J Griswold
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Explore the profile of Anthony J Griswold including associated specialties, affiliations and a list of published articles.
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66
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1394
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Recent Articles
1.
Moura S, Nasciben L, Ramirez A, Coombs L, Rivero J, Van Booven D, et al.
Alzheimers Dement
. 2025 Feb;
21(2):e70031.
PMID: 40008916
Introduction: Genome-wide association studies (GWAS) studies in Alzheimer's disease (AD) demonstrate ancestry-specific loci. Previous studies in the regulatory architecture have only been conducted in Europeans (EUs), thus studies in additional...
2.
Coughlin C, Chahar D, Lekakis M, Youssfi A, Li L, Roberts E, et al.
Blood Cancer J
. 2025 Feb;
15(1):9.
PMID: 39894894
Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline combination chemoimmunotherapy, DLBCL carries persistently poor prognosis...
3.
Barrera-Paez J, Bacman S, Balla T, Van Booven D, Gannamedi D, Stewart J, et al.
Sci Transl Med
. 2025 Jan;
17(783):eadr0792.
PMID: 39879319
Primary mitochondrial disorders are most often caused by deleterious mutations in the mitochondrial DNA (mtDNA). Here, we used a mitochondrial DddA-derived cytosine base editor (DdCBE) to introduce a compensatory edit...
4.
Avila M, Jung S, Satterstrom F, Fu J, Levy T, Sloofman L, et al.
medRxiv
. 2025 Jan;
PMID: 39830258
The past decade has seen remarkable progress in identifying genes that, when impacted by deleterious coding variation, confer high risk for autism spectrum disorder (ASD), intellectual disability, and other developmental...
5.
Wang P, Song Y, Lynn A, Miskimen K, Gulyayev A, Prough M, et al.
medRxiv
. 2025 Jan;
PMID: 39802805
Introduction: Alzheimer disease (AD) plasma biomarkers are noninvasive measures of the key amyloid beta (Aβ) and tau pathologies. Validation and generalization studies are needed to fully understand their potential for...
6.
Ramirez A, Bertholim-Nasciben L, Moura S, Coombs L, Rajabli F, DeRosa B, et al.
Res Sq
. 2024 Dec;
PMID: 39678342
Background: This study aims to elucidate ancestry-specific changes to the genomic regulatory architecture in induced pluripotent stem cell (iPSC)-derived oligodendroglia, focusing on their implications for Alzheimer's disease (AD). This work...
7.
Bertholim-Nasciben L, Nuytemans K, Van Booven D, Rajabli F, Moura S, Ramirez A, et al.
bioRxiv
. 2024 Nov;
PMID: 39484566
ε4 is the strongest genetic risk factor for Alzheimer's disease (AD) with approximately 50% of AD patients carrying at least one ε4 allele. Our group identified a protective interaction between...
8.
Cruz-Gonzalez S, Gu E, Gomez L, Mews M, Vance J, Cuccaro M, et al.
bioRxiv
. 2024 Oct;
PMID: 39464059
Epigenetic clocks that quantify rates of aging from DNA methylation patterns across the genome have emerged as a potential biomarker for risk of age-related diseases, like Alzheimer's disease (AD), and...
9.
Osborne O, Daftari M, Naranjo O, Johar A, Brooks S, Colbert B, et al.
Cell Rep
. 2024 Oct;
43(10):114848.
PMID: 39392753
Ischemic stroke and cerebral amyloid angiopathy (CAA) pose significant challenges in an aging population, particularly in post-stroke recovery. Using the 5xFAD mouse model, we explore the relationship between CAA, ischemic...
10.
Akgun B, Feliciano-Astacio B, Hamilton-Nelson K, Scott K, Rivero J, Adams L, et al.
Front Aging Neurosci
. 2024 Sep;
16:1459796.
PMID: 39295643
Introduction: Hispanic/Latino populations are underrepresented in Alzheimer Disease (AD) genetic studies. Puerto Ricans (PR), a three-way admixed (European, African, and Amerindian) population is the second-largest Hispanic group in the continental...