Annika Bestehorn
Overview
Explore the profile of Annika Bestehorn including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
33
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0
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Recent Articles
1.
Bestehorn A, von Wiren J, Zeiler C, Fesselet J, Didusch S, Forte M, et al.
Mol Cell
. 2025 Jan;
85(4):742-755.e9.
PMID: 39862867
The fidelity of immune responses depends on timely controlled and selective mRNA degradation that is largely driven by RNA-binding proteins (RBPs). It remains unclear whether stochastic or directed processes govern...
2.
Scinicariello S, Soderholm A, Schafer M, Shulkina A, Schwartz I, Hacker K, et al.
Elife
. 2023 Mar;
12.
PMID: 36961408
Tristetraprolin (TTP) is a critical negative immune regulator. It binds AU-rich elements in the untranslated-regions of many mRNAs encoding pro-inflammatory mediators, thereby accelerating their decay. A key but poorly understood...
3.
Eislmayr K, Bestehorn A, Morelli L, Borroni M, Vande Walle L, Lamkanfi M, et al.
Sci Adv
. 2022 Mar;
8(9):eabj7293.
PMID: 35235356
Interleukin-1α (IL-1α) and IL-1β are inflammatory cytokines with important roles in health and disease. They trigger the same receptor and elicit comparable cellular responses but, for poorly understood reasons, are...
4.
Gomez-Diaz C, Jonsson G, Schodl K, Deszcz L, Bestehorn A, Eislmayr K, et al.
iScience
. 2021 Nov;
24(11):103241.
PMID: 34755089
The Linear Ubiquitin Chain Assembly Complex (LUBAC), composed of HOIP, HOIL-1L, and SHARPIN, promotes tumor necrosis factor (TNF)-dependent NF-κB signaling in diverse cell types. HOIL-1L contains an Npl4 Zinc Finger...
5.
Kovarik P, Bestehorn A, Fesselet J
Front Immunol
. 2021 Oct;
12:751313.
PMID: 34603339
Regulated changes in mRNA stability are critical drivers of gene expression adaptations to immunological cues. mRNA stability is controlled mainly by RNA-binding proteins (RBPs) which can directly cleave mRNA but...
6.
Preis W, Bestehorn A, Buchner J, Haslbeck M
Cell Stress Chaperones
. 2017 Feb;
22(4):541-552.
PMID: 28214988
In humans, ten genes encode small heat shock proteins with lens αA-crystallin and αB-crystallin representing two of the most prominent members. The canonical isoforms of αA-crystallin and αB-crystallin collaborate in...