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Annegret Nath

Explore the profile of Annegret Nath including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 151
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Recent Articles
1.
Frohnert C, Hutten S, Walde S, Nath A, Kehlenbach R
PLoS One . 2014 Mar; 9(2):e88887. PMID: 24586428
In actively dividing eukaryotic cells, chromosome ends (telomeres) are subject to progressive shortening, unless they are maintained by the action of telomerase, a dedicated enzyme that adds DNA sequence repeats...
2.
Walde S, Thakar K, Hutten S, Spillner C, Nath A, Rothbauer U, et al.
Traffic . 2011 Oct; 13(2):218-33. PMID: 21995724
In vertebrates, the nuclear pore complex (NPC), the gate for transport of macromolecules between the nucleus and the cytoplasm, consists of approximately 30 different nucleoporins (Nups). The Nup and SUMO...
3.
Hilliard M, Frohnert C, Spillner C, Marcone S, Nath A, Lampe T, et al.
J Biol Chem . 2010 May; 285(29):22202-10. PMID: 20457605
The signaling molecule 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) has been described as the "anti-inflammatory prostaglandin." Here we show that substrates of the nuclear export receptor CRM1 accumulate in the nucleus in the...
4.
Arnold M, Nath A, Hauber J, Kehlenbach R
J Biol Chem . 2006 May; 281(30):20883-20890. PMID: 16704975
The Rev protein of human immunodeficiency virus type 1 is an RNA-binding protein that is required for nuclear export of unspliced and partially spliced viral mRNAs. Nuclear import of human...
5.
Arnold M, Nath A, Wohlwend D, Kehlenbach R
J Biol Chem . 2006 Jan; 281(9):5492-9. PMID: 16407315
c-Fos, a component of the transcription factor AP-1, is rapidly imported into the nucleus after translation. We established an in vitro system using digitonin-permeabilized cells to analyze nuclear import of...
6.
Pestel S, Nath A, Jungermann K, Schieferdecker H
Biochem Pharmacol . 2003 Aug; 66(4):643-52. PMID: 12906929
Prostanoids, i.e. prostaglandins and thromboxane, regulate liver-specific functions both in homeostasis and during defense reactions. For example, prostanoids are released from Kupffer cells, the resident liver macrophages, in response to...