Anne M Friel
Overview
Explore the profile of Anne M Friel including associated specialties, affiliations and a list of published articles.
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24
Citations
802
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Recent Articles
1.
Natural and Synthetic Isothiocyanates Possess Anticancer Potential Against Liver and Prostate Cancer
Crowley E, Rowan N, Faller D, Friel A
Anticancer Res
. 2019 Jul;
39(7):3469-3485.
PMID: 31262871
Background/aim: Isothiocyanates (ITCs) are phytochemicals with potential cancer-preventative properties derived from the breakdown of glucosinolates that exist in cruciferous vegetables. Studies, to date, have demonstrated that various ITCs possess the...
2.
Clark N, Friel A, Pru C, Zhang L, Shioda T, Rueda B, et al.
Cancer Biol Ther
. 2016 Jan;
17(3):262-71.
PMID: 26785864
Triple negative breast cancers (TNBCs) are highly aggressive and grow in response to sex steroid hormones despite lacking expression of the classical estrogen (E2) and progesterone (P4) receptors. Since P4...
3.
Friel A, Zhang L, Pru C, Clark N, McCallum M, Blok L, et al.
Cancer Lett
. 2014 Oct;
356(2 Pt B):434-42.
PMID: 25304370
Endometrial cancer is the leading gynecologic cancer in women in the United States with 52,630 women predicted to be diagnosed with the disease in 2014. The objective of this study...
4.
OBrien K, Rani S, Corcoran C, Wallace R, Hughes L, Friel A, et al.
Eur J Cancer
. 2013 Mar;
49(8):1845-59.
PMID: 23453937
Background: Triple-negative breast cancer (TNBC) accounts for 15-20% of breast cancers but is responsible for a disproportionate number of deaths. We investigated the relevance, in TNBC, of nano-sized exosomes expelled...
5.
McCann C, Growdon W, Kulkarni-Datar K, Curley M, Friel A, Proctor J, et al.
PLoS One
. 2011 Dec;
6(11):e28077.
PMID: 22140510
Background: Recent evidence links aberrant activation of Hedgehog (Hh) signaling with the pathogenesis of several cancers including medulloblastoma, basal cell, small cell lung, pancreatic, prostate and ovarian. This investigation was...
6.
Friel A, Crown J, ODriscoll L
Methods Mol Biol
. 2011 Sep;
784:55-75.
PMID: 21898213
Current literature provides significant evidence to support the concept that there are limited subpopulations of cells within a solid tumour that have increased tumour-initiating potential relative to the total tumour...
7.
Friel A, Zhang L, Curley M, Therrien V, Sergent P, Belden S, et al.
Reprod Biol Endocrinol
. 2010 Dec;
8:147.
PMID: 21122138
Background: Recent data provide significant evidence to support the hypothesis that there are sub-populations of cells within solid tumors that have an increased tumor initiating potential relative to the total...
8.
Corcoran C, Friel A, Duffy M, Crown J, ODriscoll L
Clin Chem
. 2010 Nov;
57(1):18-32.
PMID: 21059829
Background: Successful treatment of breast cancer is enhanced by early detection and, if possible, subsequent patient-tailored therapy. Toward this goal, it is essential to identify and understand the most relevant...
9.
Friel A, Corcoran C, Crown J, ODriscoll L
Breast Cancer Res Treat
. 2010 Jun;
123(3):613-25.
PMID: 20549336
Early detection of cancer is vital to improved overall survival rates. At present, evidence is accumulating for the clinical value of detecting occult tumor cells in peripheral blood, plasma, and...
10.
Friel A, Growdon W, McCann C, Olawaiye A, Munro E, Schorge J, et al.
Front Biosci (Elite Ed)
. 2010 Jun;
2(3):882-905.
PMID: 20515761
Uterine tumors, whether benign or malignant, are diagnosed in a significant portion of women and are associated with a number of co-morbidities that negatively impact quality of life. Uterine tumors...