Anna Worthmann
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Explore the profile of Anna Worthmann including associated specialties, affiliations and a list of published articles.
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28
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1928
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Recent Articles
11.
Worthmann A, Ridder J, Piel S, Evangelakos I, Musfeldt M, Voss H, et al.
Nat Commun
. 2024 Jan;
15(1):45.
PMID: 38167725
Dietary polyunsaturated fatty acids (PUFA) are increasingly recognized for their health benefits, whereas a high production of endogenous fatty acids - a process called de novo lipogenesis (DNL) - is...
12.
Hiefner J, Rische J, Bunders M, Worthmann A
Front Immunol
. 2023 Oct;
14:1250762.
PMID: 37799723
Adenine nucleotides (AN) are ubiquitous metabolites that regulate cellular energy metabolism and modulate cell communication and inflammation. To understand how disturbances in AN balance arise and affect cellular function, robust...
13.
Siracusa F, Schaltenberg N, Kumar Y, Lesker T, Steglich B, Liwinski T, et al.
Nat Immunol
. 2023 Aug;
24(9):1473-1486.
PMID: 37580603
Omnivorous animals, including mice and humans, tend to prefer energy-dense nutrients rich in fat over plant-based diets, especially for short periods of time, but the health consequences of this short-term...
14.
Liebold I, Meyer S, Heine M, Kuhl A, Witt J, Eissing L, et al.
Cells
. 2023 Feb;
12(3).
PMID: 36766683
Nonalcoholic fatty liver disease (NAFLD) is the most common liver pathology worldwide. In mice and humans, NAFLD progression is characterized by the appearance of TREM2-expressing macrophages in the liver. However,...
15.
Evangelakos I, Kuhl A, Baguhl M, Schlein C, John C, Rohde J, et al.
Front Cell Dev Biol
. 2022 Apr;
10:836741.
PMID: 35478959
Brown adipose tissue (BAT) has emerged as an appealing therapeutic target for cardio metabolic diseases. BAT is a heat-producing organ and upon activation substantially lowers hyperlipidemia. In response to cold...
16.
Rohde J, Fuh M, Evangelakos I, Pauly M, Schaltenberg N, Siracusa F, et al.
Metabolites
. 2022 Feb;
12(2).
PMID: 35208244
Short Chain Fatty Acids (SCFAs) are produced by the gut microbiota and are present in varying concentrations in the intestinal lumen, in feces but also in the circulatory system. By...
17.
Worthmann A, Bartelt A
Pflugers Arch
. 2021 Dec;
474(2):185-186.
PMID: 34928417
No abstract available.
18.
Dieckmann S, Strohmeyer A, Willershauser M, Maurer S, Wurst W, Marschall S, et al.
Am J Physiol Endocrinol Metab
. 2021 Dec;
322(2):E85-E100.
PMID: 34927460
Activation of uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) upon cold stimulation leads to substantial increase in energy expenditure to defend body temperature. Increases in energy expenditure after...
19.
Evangelakos I, Schwinge D, Worthmann A, John C, Roeder N, Pertzborn P, et al.
Cells
. 2021 Oct;
10(10).
PMID: 34685636
Ambient temperature is an important determinant of both the alternative bile acid synthesis pathway controlled by oxysterol 7-α hydroxylase (CYP7B1) and the progression of metabolic-associated fatty liver disease (MAFLD). Here,...
20.
Worthmann A, John C, Heeren J
Bio Protoc
. 2021 Aug;
8(13):e2916.
PMID: 34395745
The here described method can be used to estimate the uptake of orally provided cholesterol in mice. Briefly, mice are gavaged with radiolabeled cholesterol and 4 h later, organ distribution...