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Anna Supernat

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Articles 30
Citations 959
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Recent Articles
11.
Supernat A, Popeda M, Pastuszak K, Best M, Gresner P, In t Veld S, et al.
Sci Rep . 2021 Aug; 11(1):15679. PMID: 34344933
Blood platelet RNA-sequencing is increasingly used among the scientific community. Aberrant platelet transcriptome is common in cancer or cardiovascular disease, but reference data on platelet RNA content in healthy individuals...
12.
Pastuszak K, Supernat A, Best M, In t Veld S, Lapinska-Szumczyk S, Lojkowska A, et al.
Mol Oncol . 2021 May; 15(10):2688-2701. PMID: 34013585
Liquid biopsies offer a minimally invasive sample collection, outperforming traditional biopsies employed for cancer evaluation. The widely used material is blood, which is the source of tumor-educated platelets. Here, we...
13.
Luczkowska K, Sokolowska K, Taryma-Lesniak O, Pastuszak K, Supernat A, Bybjerg-Grauholm J, et al.
Sci Rep . 2021 May; 11(1):9846. PMID: 33972578
The anticancer activity of bortezomib (BTZ) has been increasingly studied in a number of indications and promising results for the use of this treatment have been shown in neuroblastoma. As...
14.
Montfort A, Barker-Clarke R, Piskorz A, Supernat A, Moore L, Al-Khalidi S, et al.
Br J Cancer . 2020 Apr; 122(12):1803-1810. PMID: 32249277
Background: In colorectal and breast cancer, the density and localisation of immune infiltrates provides strong prognostic information. We asked whether similar automated quantitation and combined analysis of immune infiltrates could...
15.
Smolle M, Czapiewski P, Lapinska-Szumczyk S, Majewska H, Supernat A, Zaczek A, et al.
Int J Mol Sci . 2019 Dec; 20(24). PMID: 31817792
Whilst the role of eukaryotic translation initiation factors (eIFs) has already been investigated in several human cancers, their role in endometrial cancer (EC) is relatively unknown. In the present retrospective...
16.
Krzyzanowska D, Supernat A, Maciag T, Matuszewska M, Jafra S
Sci Rep . 2019 Sep; 9(1):13129. PMID: 31511547
Reverse transcription quantitative PCR (RT-qPCR), a method of choice for quantification of gene expression changes, requires stably expressed reference genes for normalization of data. So far, no reference genes were...
17.
Supernat A, Vidarsson O, Steen V, Stokowy T
Sci Rep . 2018 Dec; 8(1):17851. PMID: 30552369
Testing of patients with genetics-related disorders is in progress of shifting from single gene assays to gene panel sequencing, whole-exome sequencing (WES) and whole-genome sequencing (WGS). Since WGS is unquestionably...
18.
Mouliere F, Chandrananda D, Piskorz A, Moore E, Morris J, Ahlborn L, et al.
Sci Transl Med . 2018 Nov; 10(466). PMID: 30404863
Existing methods to improve detection of circulating tumor DNA (ctDNA) have focused on genomic alterations but have rarely considered the biological properties of plasma cell-free DNA (cfDNA). We hypothesized that...
19.
Macintyre G, Goranova T, De Silva D, Ennis D, Piskorz A, Eldridge M, et al.
Nat Genet . 2018 Aug; 50(9):1262-1270. PMID: 30104763
The genomic complexity of profound copy number aberrations has prevented effective molecular stratification of ovarian cancers. Here, to decode this complexity, we derived copy number signatures from shallow whole-genome sequencing...
20.
Filipska M, Skrzypski M, Czetyrbok K, Stokowy T, Stasilojc G, Supernat A, et al.
Lung Cancer . 2018 Mar; 118:111-118. PMID: 29571988
Objectives: Overexpression of miR-192, miR-192* and miR-662 was previously found to correlate with poor prognosis of early-stage squamous cell lung cancer (SCC) patients. In this study, we investigated the relevance...