Anna J Zaczek
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Explore the profile of Anna J Zaczek including associated specialties, affiliations and a list of published articles.
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49
Citations
634
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Recent Articles
1.
Jopek M, Jopek M, Sieczczynski M, Pastuszak K, Lapinska-Szumczyk S, Jassem J, et al.
Blood Adv
. 2024 Dec;
9(5):979-989.
PMID: 39715465
Ovarian cancer (OC) presents a diagnostic challenge, often resulting in poor patient outcomes. Platelet RNA sequencing, which reflects host response to disease, shows promise for earlier OC detection. This study...
2.
Popeda M, Kowalski K, Wenta T, Beznoussenko G, Rychlowski M, Mironov A, et al.
Exp Mol Med
. 2024 Sep;
56(9):2016-2032.
PMID: 39218980
Micronuclei (MN) can form through many mechanisms, including the breakage of aberrant cytokinetic chromatin bridges. The frequent observation of MN in tumors suggests that they might not merely be passive...
3.
Jopek M, Pastuszak K, Sieczczynski M, Cygert S, Zaczek A, Rondina M, et al.
Mol Oncol
. 2024 Jun;
18(11):2743-2754.
PMID: 38887841
Liquid biopsy demonstrates excellent potential in patient management by providing a minimally invasive and cost-effective approach to detecting and monitoring cancer, even at its early stages. Due to the complexity...
4.
Pastuszak K, Sieczczynski M, Dziegielewska M, Wolniak R, Drewnowska A, Korpal M, et al.
Sci Rep
. 2024 May;
14(1):11057.
PMID: 38744942
Circulating tumor cells (CTCs) are tumor cells that separate from the solid tumor and enter the bloodstream, which can cause metastasis. Detection and enumeration of CTCs show promising potential as...
5.
Topa J, Zaczek A, Markiewicz A
Methods Mol Biol
. 2024 Jan;
2752:43-52.
PMID: 38194026
Circulating tumor cells (CTCs) undergoing epithelial-mesenchymal transition (EMT) may exhibit more aggressive features than epithelial CTCs and are more frequently observed during disease progression. Therefore, detection and characterization of both...
6.
Muchlinska A, Wenta R, Scinska W, Markiewicz A, Suchodolska G, Senkus E, et al.
Cancers (Basel)
. 2023 Aug;
15(16).
PMID: 37627197
Circulating tumor cells (CTCs) and circulating cancer-associated fibroblasts (cCAFs) have been individually considered strong indicators of cancer progression. However, technical limitations have prevented their simultaneous analysis in the context of...
7.
Cygert S, Pastuszak K, Gorski F, Sieczczynski M, Juszczyk P, Rutkowski A, et al.
Cancers (Basel)
. 2023 May;
15(8).
PMID: 37190262
Liquid biopsies offer minimally invasive diagnosis and monitoring of cancer disease. This biosource is often analyzed using sequencing, which generates highly complex data that can be used using machine learning...
8.
Gao Y, Liu C, Li H, Xiong X, Li G, In t Veld S, et al.
Protein Cell
. 2023 Mar;
14(6):579-590.
PMID: 36905391
Platelets are reprogrammed by cancer via a process called education, which favors cancer development. The transcriptional profile of tumor-educated platelets (TEPs) is skewed and therefore practicable for cancer detection. This...
9.
Muchlinska A, Smentoch J, Zaczek A, Bednarz-Knoll N
Cancers (Basel)
. 2022 Sep;
14(17).
PMID: 36077716
Tumor dissemination is one of the most-investigated steps of tumor progression, which in recent decades led to the rapid development of liquid biopsy aiming to analyze circulating tumor cells (CTCs),...
10.
In t Veld S, Arkani M, Post E, Antunes-Ferreira M, DAmbrosi S, Vessies D, et al.
Cancer Cell
. 2022 Sep;
40(9):999-1009.e6.
PMID: 36055228
Cancer patients benefit from early tumor detection since treatment outcomes are more favorable for less advanced cancers. Platelets are involved in cancer progression and are considered a promising biosource for...