Anna M Scarborough
Overview
Explore the profile of Anna M Scarborough including associated specialties, affiliations and a list of published articles.
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4
Citations
141
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Recent Articles
1.
Devlin A, Shukla A, Ruiz J, Barnes S, Govindan A, Hunter O, et al.
Nat Commun
. 2022 Dec;
13(1):7447.
PMID: 36460671
Control of RNA Polymerase II (pol II) elongation is a critical component of gene expression in mammalian cells. The PNUTS-PP1 complex controls elongation rates, slowing pol II after polyadenylation sites...
2.
Scarborough A, Govindan A, Conrad N
Methods Mol Biol
. 2022 Jul;
2537:263-284.
PMID: 35895270
Intron retention (IR) regulates gene expression to control fundamental biological processes like metabolism, differentiation, and cell cycle. Despite a wide variety of genes controlled by IR, few techniques are available...
3.
Scarborough A, Flaherty J, Hunter O, Liu K, Kumar A, Xing C, et al.
Elife
. 2021 May;
10.
PMID: 33949310
S-adenosylmethionine (SAM) is the methyl donor for nearly all cellular methylation events. Cells regulate intracellular SAM levels through intron detention of MAT2A, the only SAM synthetase expressed in most cells....
4.
Doxtader K, Wang P, Scarborough A, Seo D, Conrad N, Nam Y
Mol Cell
. 2018 Sep;
71(6):1001-1011.e4.
PMID: 30197297
S-adenosylmethionine (SAM) is an essential metabolite that acts as a cofactor for most methylation events in the cell. The N-methyladenosine (mA) methyltransferase METTL16 controls SAM homeostasis by regulating the abundance...