Kuanqing Liu
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Explore the profile of Kuanqing Liu including associated specialties, affiliations and a list of published articles.
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15
Citations
1182
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Recent Articles
1.
She F, Liu K, Anderson B, Pisithkul T, Li Y, Fung D, et al.
mBio
. 2025 Feb;
:e0379824.
PMID: 39998177
Importance: In this study, we reveal that pyruvate kinase, a key glycolytic enzyme, primarily generates GTP from GDP in , relative to other nucleotide triphosphates, such as ATP. This finding,...
2.
She F, Liu K, Anderson B, Pisithkul T, Li Y, Fung D, et al.
bioRxiv
. 2025 Jan;
PMID: 39763737
Importance: In this study, we reveal pyruvate kinase, a key glycolytic enzyme, primarily generates GTP from GDP in , relatively to other trinucleotides such as ATP. This finding, uncovered through...
3.
Scarborough A, Flaherty J, Hunter O, Liu K, Kumar A, Xing C, et al.
Elife
. 2021 May;
10.
PMID: 33949310
S-adenosylmethionine (SAM) is the methyl donor for nearly all cellular methylation events. Cells regulate intracellular SAM levels through intron detention of MAT2A, the only SAM synthetase expressed in most cells....
4.
Liu K, Santos D, Hussmann J, Wang Y, Sutter B, Weissman J, et al.
Cell Rep
. 2021 Mar;
34(10):108825.
PMID: 33691096
N-methyladenosine (mA) is a conserved ribonucleoside modification that regulates many facets of RNA metabolism. Using quantitative mass spectrometry, we find that the universally conserved tandem adenosines at the 3' end...
5.
Liu K, Sutter B, Tu B
Nat Commun
. 2021 Jan;
12(1):57.
PMID: 33397945
Autophagy catabolizes cellular constituents to promote survival during nutrient deprivation. Yet, a metabolic comprehension of this recycling operation, despite its crucial importance, remains incomplete. Here, we uncover a specific metabolic...
6.
Anderson B, Liu K, Wolak C, Dubiel K, She F, Satyshur K, et al.
Elife
. 2019 Sep;
8.
PMID: 31552824
The alarmone (p)ppGpp regulates diverse targets, yet its target specificity and evolution remain poorly understood. Here, we elucidate the mechanism by which basal (p)ppGpp inhibits the purine salvage enzyme HPRT...
7.
Weiss C, Hoberg J, Liu K, Tu B, Winkler W
J Bacteriol
. 2019 May;
201(16).
PMID: 31138629
The synthesis of signaling molecules is one strategy bacteria employ to sense alterations in their environment and rapidly adjust to those changes. In Gram-negative bacteria, bis-(3'-5')-cyclic dimeric GMP (c-di-GMP) regulates...
8.
Orr M, Weiss C, Severin G, Turdiev H, Kim S, Turdiev A, et al.
J Bacteriol
. 2018 Sep;
200(24).
PMID: 30249708
Bis-(3'-5')-cyclic dimeric GMP (c-di-GMP) is a bacterial second messenger that regulates processes, such as biofilm formation and virulence. During degradation, c-di-GMP is first linearized to 5'-phosphoguanylyl-(3',5')-guanosine (pGpG) and subsequently hydrolyzed...
9.
Pendleton K, Chen B, Liu K, Hunter O, Xie Y, Tu B, et al.
Cell
. 2017 May;
169(5):824-835.e14.
PMID: 28525753
Maintenance of proper levels of the methyl donor S-adenosylmethionine (SAM) is critical for a wide variety of biological processes. We demonstrate that the N-adenosine methyltransferase METTL16 regulates expression of human...
10.
Li W, Bouveret E, Zhang Y, Liu K, Wang J, Weisshaar J
Mol Microbiol
. 2015 Oct;
99(3):571-85.
PMID: 26480956
During amino acid starvation, bacterial cells rapidly synthesize the nucleotides (p)ppGpp, causing a massive re-programming of the transcriptional profile known as the stringent response. The (p)ppGpp synthase RelA is activated...