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Anna J Zaczek

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Articles 49
Citations 634
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Recent Articles
11.
Mieczkowski K, Kitowska K, Braun M, Galikowska-Bogut B, Gorska-Arcisz M, Piasecka D, et al.
Mol Oncol . 2022 Jun; 16(15):2823-2842. PMID: 35726195
We have recently demonstrated that fibroblast growth factor receptor 2 (FGFR2)-mediated signalling alters progesterone receptor (PR) activity and response of oestrogen receptor α (ER)-positive (ER+) breast cancer (BCa) cell lines...
12.
Muchlinska A, Nagel A, Popeda M, Szade J, Niemira M, Zielinski J, et al.
Cell Mol Biol Lett . 2022 Jun; 27(1):45. PMID: 35690734
Background: Cancer-associated fibroblasts (CAFs) have been shown to support tumor development in a variety of cancers. Different markers were applied to classify CAFs in order to elucidate their impact on...
13.
Nagel A, Popeda M, Muchlinska A, Sadej R, Szade J, Zielinski J, et al.
Cancers (Basel) . 2022 Apr; 14(8). PMID: 35454913
Background: Cancer-associated fibroblasts (CAFs) are the most abundant cell type in the tumor microenvironment (TME). Estrogen receptor alpha 36 (ERα36), the alternatively spliced variant of ERα, is described as an...
14.
Panasiuk M, Zimmer K, Czarnota A, Narajczyk M, Peszynska-Sularz G, Chraniuk M, et al.
J Nanobiotechnology . 2022 Mar; 20(1):160. PMID: 35351156
Background: Immunotherapy is emerging as a powerful treatment approach for several types of cancers. Modulating the immune system to specifically target cancer cells while sparing healthy cells, is a very...
15.
Topa J, Gresner P, Zaczek A, Markiewicz A
Cell Mol Life Sci . 2022 Jan; 79(2):81. PMID: 35048186
Circulating tumor cells (CTCs) mediate dissemination of solid tumors and can be an early sign of disease progression. Moreover, they show a great potential in terms of non-invasive, longitudinal monitoring...
16.
Bednarz-Knoll N, Popeda M, Kryczka T, Kozakiewicz B, Pogoda K, Szade J, et al.
Br J Cancer . 2021 Dec; 126(3):464-471. PMID: 34857895
Background: Platelets support tumour progression. However, their prognostic significance and relation to circulating tumour cells (CTCs) in operable breast cancer (BrCa) are still scarcely known and, thus, merit further investigation....
17.
Nastaly P, Smentoch J, Popeda M, Martini E, Maiuri P, Zaczek A, et al.
J Pers Med . 2021 Nov; 11(11). PMID: 34834440
Tumor-to-stroma ratio (TSR) is a prognostic factor that expresses the relative amounts of tumor and intratumoral stroma. In this study, its clinical and molecular relevance was evaluated in prostate cancer...
18.
Lukasiewicz M, Pastuszak K, Lapinska-Szumczyk S, Rozanski R, In t Veld S, Bienkowski M, et al.
Cancers (Basel) . 2021 Nov; 13(22). PMID: 34830891
Background: Liquid biopsy is a minimally invasive collection of a patient body fluid sample. In oncology, they offer several advantages compared to traditional tissue biopsies. However, the potential of this...
19.
Supernat A, Popeda M, Pastuszak K, Best M, Gresner P, In t Veld S, et al.
Sci Rep . 2021 Aug; 11(1):15679. PMID: 34344933
Blood platelet RNA-sequencing is increasingly used among the scientific community. Aberrant platelet transcriptome is common in cancer or cardiovascular disease, but reference data on platelet RNA content in healthy individuals...
20.
Pastuszak K, Supernat A, Best M, In t Veld S, Lapinska-Szumczyk S, Lojkowska A, et al.
Mol Oncol . 2021 May; 15(10):2688-2701. PMID: 34013585
Liquid biopsies offer a minimally invasive sample collection, outperforming traditional biopsies employed for cancer evaluation. The widely used material is blood, which is the source of tumor-educated platelets. Here, we...