Anna A Lobas
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Explore the profile of Anna A Lobas including associated specialties, affiliations and a list of published articles.
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26
Citations
181
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Recent Articles
1.
Fedorov I, Bubis J, Kazakova E, Lobas A, Ivanov M, Emekeeva D, et al.
Anal Bioanal Chem
. 2024 May;
416(18):4083-4089.
PMID: 38744720
Advances in high-throughput high-resolution mass spectrometry and the development of thermal proteome profiling approach (TPP) have made it possible to accelerate a drug target search. Since its introduction in 2014,...
2.
Lobas A, Saei A, Lyu H, Zubarev R, Gorshkov M
ACS Pharmacol Transl Sci
. 2024 Mar;
7(3):787-796.
PMID: 38481686
Rapamycin is a natural antifungal, immunosuppressive, and antiproliferative compound that allosterically inhibits mTOR complex 1. The ubiquitin-proteasome system (UPS) responsible for protein turnover is usually not listed among the pathways...
3.
Levitsky L, Ivanov M, Goncharov A, Kliuchnikova A, Bubis J, Lobas A, et al.
J Proteome Res
. 2023 May;
22(6):1695-1711.
PMID: 37158322
The proteogenomic search pipeline developed in this work has been applied for reanalysis of 40 publicly available shotgun proteomic datasets from various human tissues comprising more than 8000 individual LC-MS/MS...
4.
Lobas A, Solovyeva E, Levitsky L, Goncharov A, Lyssuk E, Larin S, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768787
Alternative splicing is one of the main regulation pathways in living cells beyond simple changes in the level of protein expression. Most of the approaches proposed in proteomics for the...
5.
Solovyeva E, Bubis J, Tarasova I, Lobas A, Ivanov M, Nazarov A, et al.
Biochemistry (Mosc)
. 2022 Dec;
87(11):1342-1353.
PMID: 36509723
Protein quantitation in tissue cells or physiological fluids based on liquid chromatography/mass spectrometry is one of the key sources of information on the mechanisms of cell functioning during chemotherapeutic treatment....
6.
Levitsky L, Kuznetsova K, Kliuchnikova A, Ilina I, Goncharov A, Lobas A, et al.
J Proteome Res
. 2022 May;
21(6):1438-1448.
PMID: 35536917
Mass spectrometry-based proteome analysis implies matching the mass spectra of proteolytic peptides to amino acid sequences predicted from genomic sequences. Reliability of peptide variant identification in proteogenomic studies is often...
7.
Lobas A, Solovyeva E, Saparbaev E, Gorshkov M, Boyarkin O
Talanta
. 2021 Jun;
232:122412.
PMID: 34074402
Identification of isomeric biomolecules remains a challenging analytical problem. A recently developed spectroscopic method that combines UV photofragmentation and mass spectrometry for fingerprinting of cold ions (2D UV-MS), has already...
8.
Ivanov M, Bubis J, Gorshkov V, Tarasova I, Levitsky L, Lobas A, et al.
Anal Chem
. 2020 Feb;
92(6):4326-4333.
PMID: 32077687
Proteome characterization relies heavily on tandem mass spectrometry (MS/MS) and is thus associated with instrumentation complexity, lengthy analysis time, and limited duty cycle. It was always tempting to implement approaches...
9.
Solovyeva E, Kopysov V, Pereverzev A, Lobas A, Moshkovskii S, Gorshkov M, et al.
Anal Chem
. 2019 May;
91(10):6709-6715.
PMID: 31042365
Identification of isomeric amino acid residues in peptides and proteins is challenging but often highly desired in proteomics. One of the practically important cases that require isomeric assignments is that...
10.
Srzentic K, Nagornov K, Fornelli L, Lobas A, Ayoub D, Kozhinov A, et al.
Anal Chem
. 2018 Sep;
90(21):12527-12535.
PMID: 30252447
Pairing light and heavy chains in monoclonal antibodies (mAbs) using top-down (TD) or middle-down (MD) mass spectrometry (MS) may complement the sequence information on single chains provided by high-throughput genomic...