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Anjun Ma

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Articles 61
Citations 1033
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Recent Articles
1.
Yu Y, Wang S, Li J, Yu M, McCrocklin K, Kang J, et al.
Res Sq . 2025 Jan; PMID: 39877090
The spatial arrangement of cells plays a pivotal role in shaping tissue functions in various biological systems and diseased microenvironments. However, it is still under-investigated of the topological coordinating rules...
2.
Liu Z, Sun Y, Li Y, Ma A, Willaims N, Jahanbahkshi S, et al.
Adv Sci (Weinh) . 2024 Sep; 11(41):e2403393. PMID: 39225619
Microbes are extensively present among various cancer tissues and play critical roles in carcinogenesis and treatment responses. However, the underlying relationships between intratumoral microbes and tumors remain poorly understood. Here,...
3.
Chang Y, Liu J, Jiang Y, Ma A, Yeo Y, Guo Q, et al.
Nat Commun . 2024 Aug; 15(1):7467. PMID: 39209833
Spatial omics technologies decipher functional components of complex organs at cellular and subcellular resolutions. We introduce Spatial Graph Fourier Transform (SpaGFT) and apply graph signal processing to a wide range...
4.
Li Y, Ma A, Wang Y, Guo Q, Wang C, Fu H, et al.
Brief Bioinform . 2024 Jul; 25(5). PMID: 39082647
Deciphering the intricate relationships between transcription factors (TFs), enhancers, and genes through the inference of enhancer-driven gene regulatory networks (eGRNs) is crucial in understanding gene regulatory programs in a complex...
5.
Meng W, Xu J, Huang Y, Wang C, Song Q, Ma A, et al.
medRxiv . 2024 Jul; PMID: 39040206
Alzheimer's Disease (AD) is a complex neurodegenerative disorder significantly influenced by sex differences, with approximately two-thirds of AD patients being women. Characterizing the sex-specific AD progression and identifying its progression...
6.
Wang C, Acosta D, McNutt M, Bian J, Ma A, Fu H, et al.
Nat Commun . 2024 Jun; 15(1):4710. PMID: 38844475
Alzheimer's Disease (AD) pathology has been increasingly explored through single-cell and single-nucleus RNA-sequencing (scRNA-seq & snRNA-seq) and spatial transcriptomics (ST). However, the surge in data demands a comprehensive, user-friendly repository....
7.
Li Y, Wang Y, Wang C, Ma A, Ma Q, Liu B
Patterns (N Y) . 2024 Mar; 5(3):100927. PMID: 38487805
In this study, we introduce TESA (weighted two-stage alignment), an innovative motif prediction tool that refines the identification of DNA-binding protein motifs, essential for deciphering transcriptional regulatory mechanisms. Unlike traditional...
8.
Chang Y, Liu J, Jiang Y, Ma A, Yeo Y, Guo Q, et al.
Res Sq . 2024 Feb; PMID: 38410424
Spatial omics technologies are capable of deciphering detailed components of complex organs or tissue in cellular and subcellular resolution. A robust, interpretable, and unbiased representation method for spatial omics is...
9.
Li J, Ma A, Zhang R, Chen Y, Bolyard C, Zhao B, et al.
Cancer Immunol Immunother . 2024 Feb; 73(3):52. PMID: 38349405
Introduction: As one of the major components of the tumor microenvironment, tumor-associated macrophages (TAMs) possess profound inhibitory activity against T cells and facilitate tumor escape from immune checkpoint blockade therapy....
10.
Wang C, Ma A, Li Y, McNutt M, Zhang S, Zhu J, et al.
Cancer Res Commun . 2024 Jan; 4(2):293-302. PMID: 38259095
Significance: Studying the tumor microbiome in high-throughput sequencing data is challenging because of the extremely sparse data matrices, heterogeneity, and high likelihood of contamination. We present a new deep learning...