Anjali P Kusumbe
Overview
Explore the profile of Anjali P Kusumbe including associated specialties, affiliations and a list of published articles.
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30
Citations
3307
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Recent Articles
21.
Itkin T, Gur-Cohen S, Spencer J, Schajnovitz A, Ramasamy S, Kusumbe A, et al.
Nature
. 2016 Jul;
538(7624):274.
PMID: 27437586
No abstract available.
22.
Itkin T, Gur-Cohen S, Spencer J, Schajnovitz A, Ramasamy S, Kusumbe A, et al.
Nature
. 2016 Apr;
532(7599):323-8.
PMID: 27074509
Bone marrow endothelial cells (BMECs) form a network of blood vessels that regulate both leukocyte trafficking and haematopoietic stem and progenitor cell (HSPC) maintenance. However, it is not clear how...
23.
Kusumbe A, Ramasamy S, Itkin T, Mae M, Langen U, Betsholtz C, et al.
Nature
. 2016 Apr;
532(7599):380-4.
PMID: 27074508
Blood vessels define local microenvironments in the skeletal system, play crucial roles in osteogenesis and provide niches for haematopoietic stem cells. The properties of niche-forming vessels and their changes in...
24.
Kusumbe A, Ramasamy S, Starsichova A, Adams R
Nat Protoc
. 2015 Oct;
10(12):1904-14.
PMID: 26513669
High-resolution confocal imaging is a vital tool for analyzing the 3D architecture and detailed spatial distribution of cells in situ. However, imaging of skeletal tissue has remained technically challenging because...
25.
Ramasamy S, Kusumbe A, Adams R
Trends Cell Biol
. 2014 Dec;
25(3):148-57.
PMID: 25529933
Endothelial cells (ECs) form an extensive network of blood vessels that has numerous essential functions in the vertebrate body. In addition to their well-established role as a versatile transport network,...
26.
27.
Ramasamy S, Kusumbe A, Wang L, Adams R
Nature
. 2014 Mar;
507(7492):376-380.
PMID: 24647000
Blood vessel growth in the skeletal system and osteogenesis seem to be coupled, suggesting the existence of molecular crosstalk between endothelial and osteoblastic cells. Understanding the nature of the mechanisms...
28.
Kusumbe A, Ramasamy S, Adams R
Nature
. 2014 Mar;
507(7492):323-328.
PMID: 24646994
The mammalian skeletal system harbours a hierarchical system of mesenchymal stem cells, osteoprogenitors and osteoblasts sustaining lifelong bone formation. Osteogenesis is indispensable for the homeostatic renewal of bone as well...
29.
Bapat S, Krishnan A, Ghanate A, Kusumbe A, Kalra R
Cancer Res
. 2010 Jun;
70(12):4809-19.
PMID: 20530682
Multiple, dissimilar genetic defects in cancers of the same origin contribute to heterogeneity in tumor phenotypes and therapeutic responses of patients, yet the associated molecular mechanisms remain elusive. Here, we...
30.
Kusumbe A, Bapat S
Cancer Res
. 2009 Dec;
69(24):9245-53.
PMID: 19951996
Tumor formation involves substantial cell division and genetic instability, but the relationship between quiescent cancer stem cells (CSC) and dividing progenitors in these events is poorly understood. Likewise, the implication...