Anjali P Kusumbe
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Explore the profile of Anjali P Kusumbe including associated specialties, affiliations and a list of published articles.
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30
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3307
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Recent Articles
11.
Singh A, Veeriah V, Xi P, Labella R, Chen J, Romeo S, et al.
JCI Insight
. 2019 Jul;
4(13).
PMID: 31292293
Bone provides supportive microenvironments for hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) and is a frequent site of metastasis. While incidences of bone metastases increase with age, the...
12.
Romeo S, Alawi K, Rodrigues J, Singh A, Kusumbe A, Ramasamy S
Nat Cell Biol
. 2019 Apr;
21(4):430-441.
PMID: 30936475
Growth plate cartilage contributes to the generation of a large variety of shapes and sizes of skeletal elements in the mammalian system. The removal of cartilage and how this process...
13.
Duarte D, Hawkins E, Akinduro O, Ang H, De Filippo K, Kong I, et al.
Cell Stem Cell
. 2017 Dec;
22(1):64-77.e6.
PMID: 29276143
Bone marrow vascular niches sustain hematopoietic stem cells (HSCs) and are drastically remodeled in leukemia to support pathological functions. Acute myeloid leukemia (AML) cells produce angiogenic factors, which likely contribute...
14.
Langen U, Pitulescu M, Kim J, Enriquez-Gasca R, Sivaraj K, Kusumbe A, et al.
Nat Cell Biol
. 2017 Feb;
19(3):189-201.
PMID: 28218908
Blood vessels in the mammalian skeletal system control bone formation and support haematopoiesis by generating local niche environments. While a specialized capillary subtype, termed type H, has been recently shown...
15.
Bixel M, Kusumbe A, Ramasamy S, Sivaraj K, Butz S, Vestweber D, et al.
Cell Rep
. 2017 Feb;
18(7):1804-1816.
PMID: 28199850
Measurements of flow velocities at the level of individual arterial vessels and sinusoidal capillaries are crucial for understanding the dynamics of hematopoietic stem and progenitor cell homing in the bone...
16.
Allocca G, Kusumbe A, Ramasamy S, Wang N
Bonekey Rep
. 2016 Dec;
5:851.
PMID: 28018584
Confocal and two-photon microscopy has been widely used in bone research to not only produce high quality, three-dimensional images but also to provide valuable structural and quantitative information. In this...
17.
Ramasamy S, Kusumbe A, Schiller M, Zeuschner D, Bixel M, Milia C, et al.
Nat Commun
. 2016 Dec;
7:13601.
PMID: 27922003
While blood vessels play important roles in bone homeostasis and repair, fundamental aspects of vascular function in the skeletal system remain poorly understood. Here we show that the long bone...
18.
Kusumbe A
J Bone Oncol
. 2016 Oct;
5(3):112-116.
PMID: 27761369
The vasculature of the skeletal system regulates osteogenesis and hematopoiesis, in addition to its primary function as a transportation network. Recent studies suggest that the vasculature in bone regulates multiple...
19.
Kusumbe A, Ramasamy S, Itkin T, Mae M, Langen U, Betsholtz C, et al.
Nature
. 2016 Sep;
539(7628):314.
PMID: 27626373
No abstract available.
20.
Ramasamy S, Kusumbe A, Itkin T, Gur-Cohen S, Lapidot T, Adams R
Annu Rev Cell Dev Biol
. 2016 Aug;
32:649-675.
PMID: 27576121
In addition to their conventional role as a versatile transport system, blood vessels provide signals controlling organ development, regeneration, and stem cell behavior. In the skeletal system, certain capillaries support...