Anjali P Kusumbe
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Explore the profile of Anjali P Kusumbe including associated specialties, affiliations and a list of published articles.
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3307
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Recent Articles
1.
Glaviano A, Lau H, Carter L, Lee E, Lam H, Okina E, et al.
J Hematol Oncol
. 2025 Jan;
18(1):6.
PMID: 39806516
The tumor microenvironment (TME) is integral to cancer progression, impacting metastasis and treatment response. It consists of diverse cell types, extracellular matrix components, and signaling molecules that interact to promote...
2.
Xu Z, Kusumbe A, Cai H, Wan Q, Chen J
J Biomed Mater Res B Appl Biomater
. 2023 Mar;
111(7):1434-1446.
PMID: 36880538
One specific capillary subtype, termed type H vessel, has been found with unique functional characteristics in coupling angiogenesis with osteogenesis. Researchers have fabricated a variety of tissue engineering scaffolds to...
3.
Biswas L, Chen J, De Angelis J, Singh A, Owen-Woods C, Ding Z, et al.
Cell
. 2023 Jan;
186(2):382-397.e24.
PMID: 36669473
Blood and lymphatic vessels form a versatile transport network and provide inductive signals to regulate tissue-specific functions. Blood vessels in bone regulate osteogenesis and hematopoiesis, but current dogma suggests that...
4.
Kumar N, Saraber P, Ding Z, Kusumbe A
Front Immunol
. 2022 Jan;
12:798211.
PMID: 34975909
The bones and joints in the skeletal system are composed of diverse cell types, including vascular niches, bone cells, connective tissue cells and mineral deposits and regulate whole-body homeostasis. The...
5.
Stucker S, De Angelis J, Kusumbe A
Front Physiol
. 2021 Mar;
12:624928.
PMID: 33767633
The endocrine system consists of several highly vascularized glands that produce and secrete hormones to maintain body homeostasis and regulate a range of bodily functions and processes, including growth, metabolism...
6.
Chen J, Sivan U, Tan S, Lippo L, De Angelis J, Labella R, et al.
Sci Adv
. 2021 Feb;
7(6).
PMID: 33536212
Blood vessels provide supportive microenvironments for maintaining tissue functions. Age-associated vascular changes and their relation to tissue aging and pathology are poorly understood. Here, we perform 3D imaging of young...
7.
Stucker S, Chen J, Watt F, Kusumbe A
Front Cell Dev Biol
. 2020 Dec;
8:602269.
PMID: 33324652
The bone marrow (BM) vascular niche microenvironments harbor stem and progenitor cells of various lineages. Bone angiogenesis is distinct and involves tissue-specific signals. The nurturing vascular niches in the BM...
8.
Chen J, Lippo L, Labella R, Tan S, Marsden B, Dustin M, et al.
EMBO J
. 2020 Nov;
40(1):e105242.
PMID: 33215738
Age-associated alterations of the hormone-secreting endocrine system cause organ dysfunction and disease states. However, the cell biology of endocrine tissue ageing remains poorly understood. Here, we perform comparative 3D imaging...
9.
Chen J, Hendriks M, Chatzis A, Ramasamy S, Kusumbe A
J Bone Miner Res
. 2020 Aug;
35(11):2103-2120.
PMID: 32845550
Bone vasculature and bone marrow vascular niches supply oxygen, nutrients, and secrete angiocrine factors required for the survival, maintenance, and self-renewal of stem and progenitor cells. In the skeletal system,...
10.
Sivan U, De Angelis J, Kusumbe A
Open Biol
. 2019 Oct;
9(10):190144.
PMID: 31575330
Skeletal vasculature plays a central role in the maintenance of microenvironments for osteogenesis and haematopoiesis. In addition to supplying oxygen and nutrients, vasculature provides a number of inductive factors termed...