Anja Stefanski
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Explore the profile of Anja Stefanski including associated specialties, affiliations and a list of published articles.
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34
Citations
459
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Recent Articles
1.
Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways
Damiecki M, Naha R, Schaumkessel Y, Westhoff P, Atanelov N, Stefanski A, et al.
Life Sci Alliance
. 2024 Oct;
7(12).
PMID: 39393820
Mitochondria play central roles in metabolism and metabolic disorders such as type 2 diabetes. MIC26, a mitochondrial contact site and cristae organising system complex subunit, was linked to diabetes and...
2.
Levy T, Voeltzke K, Hruby L, Alasad K, Bas Z, Snaebjornsson M, et al.
Nat Commun
. 2024 May;
15(1):4083.
PMID: 38744825
Energetic stress compels cells to evolve adaptive mechanisms to adjust their metabolism. Inhibition of mTOR kinase complex 1 (mTORC1) is essential for cell survival during glucose starvation. How mTORC1 controls...
3.
Qin N, Paisana E, Picard D, Leprivier G, Langini M, Custodia C, et al.
J Neurooncol
. 2023 Nov;
165(2):329-342.
PMID: 37976029
Purpose: Primary brain tumors are a leading cause of cancer-related death in children, and medulloblastoma is the most common malignant pediatric brain tumor. The current molecular characterization of medulloblastoma is...
4.
Wrobel T, Brilhaus D, Stefanski A, Stuhler K, Weber A, Linka N
Front Plant Sci
. 2023 Oct;
14:1182105.
PMID: 37868318
In this work, we studied castor-oil plant as a classical system for endosperm reserve breakdown. The seeds of castor beans consist of a centrally located embryo with the two thin...
5.
Picard D, Felsberg J, Langini M, Stachura P, Qin N, Macas J, et al.
Acta Neuropathol
. 2023 Sep;
146(4):551-564.
PMID: 37656187
Pilocytic astrocytoma (PA), the most common pediatric brain tumor, is driven by aberrant mitogen-activated protein kinase signaling most commonly caused by BRAF gene fusions or activating mutations. While 5-year overall...
6.
Eberle R, Coronado M, Gering I, Sommerhage S, Korostov K, Stefanski A, et al.
PLoS One
. 2023 Aug;
18(8):e0288138.
PMID: 37603556
The primary function of virus proteases is the proteolytic processing of the viral polyprotein. These enzymes can also cleave host cell proteins, which is important for viral pathogenicity, modulation of...
7.
Macorano L, Binny T, Spiegl T, Klimenko V, Singer A, Oberleitner L, et al.
Proc Natl Acad Sci U S A
. 2023 Jun;
120(27):e2221595120.
PMID: 37364116
The chromatophores in are evolutionary-early-stage photosynthetic organelles. Biological processes in chromatophores depend on a combination of chromatophore and nucleus-encoded proteins. Interestingly, besides proteins carrying chromatophore-targeting signals, a large arsenal of...
8.
Sohngen C, Thomas D, Skowron M, Bremmer F, Eckstein M, Stefanski A, et al.
FEBS J
. 2023 May;
290(20):4864-4876.
PMID: 37254618
Alternative therapeutic options targeting urologic malignancies, such as germ cell tumours, as well as urothelial, renal and prostate carcinomas, are still urgently needed. The membrane protein CD24 represents a promising...
9.
Skowron M, Kotthoff M, Bremmer F, Ruhnke K, Parmaksiz F, Richter A, et al.
Mol Med
. 2023 Mar;
29(1):40.
PMID: 36991316
Background: Being the standard-of-care for four decades, cisplatin-based chemotherapy is highly efficient in treating germ cell tumors (GCT). However, often refractory patients present with a remaining (resistant) yolk-sac tumor (YST(-R))...
10.
Marquardt V, Theruvath J, Pauck D, Picard D, Qin N, Blumel L, et al.
J Immunother Cancer
. 2023 Jan;
11(1).
PMID: 36639156
Background: While major advances have been made in improving the quality of life and survival of children with most forms of medulloblastoma (MB), those with MYC-driven tumors (Grp3-MB) still suffer...