Daniel Picard
Overview
Explore the profile of Daniel Picard including associated specialties, affiliations and a list of published articles.
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Articles
73
Citations
1476
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Recent Articles
1.
Pauck D, Picard D, Maue M, Taban K, Marquardt V, Blumel L, et al.
Pharmacol Res
. 2025 Feb;
213:107660.
PMID: 39961404
Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant embryonal brain tumor driven by genetic alterations inactivating the SMARCB1 or, less commonly, the SMARCA4 gene. Large-scale molecular profiling studies have identified...
2.
Reiche L, Plaack B, Lehmkuhl M, Weyers V, Gruchot J, Picard D, et al.
Microbes Infect
. 2024 Nov;
:105460.
PMID: 39577621
Gliomas are the most common parenchymal tumors of the central nervous system (CNS). With regard to their still unclear etiology, several recent studies have provided evidence of a new category...
3.
Jeising S, Nickel A, Trubel J, Felsberg J, Picard D, Leprivier G, et al.
J Neurooncol
. 2024 Jul;
169(3):613-623.
PMID: 38985431
Purpose: Brain metastases represent the most common intracranial tumors in adults and are associated with a poor prognosis. We used a personalized in vitro drug screening approach to characterize individual...
4.
Levy T, Voeltzke K, Hruby L, Alasad K, Bas Z, Snaebjornsson M, et al.
Nat Commun
. 2024 May;
15(1):4083.
PMID: 38744825
Energetic stress compels cells to evolve adaptive mechanisms to adjust their metabolism. Inhibition of mTOR kinase complex 1 (mTORC1) is essential for cell survival during glucose starvation. How mTORC1 controls...
5.
Kocher D, Cao L, Guiho R, Langhammer M, Lai Y, Becker P, et al.
J Neurooncol
. 2024 Apr;
168(2):317-332.
PMID: 38630384
Introduction: Patients with pediatric low-grade gliomas (pLGGs), the most common primary brain tumors in children, can often benefit from MAPK inhibitor (MAPKi) treatment. However, rapid tumor regrowth, also referred to...
6.
Blumel L, Bernardi F, Picard D, Diaz J, Jepsen V, Hasselmann R, et al.
Haematologica
. 2024 Mar;
109(7):2290-2296.
PMID: 38426288
No abstract available.
7.
Vogt M, Dienstbier N, Schliehe-Diecks J, Scharov K, Tu J, Gebing P, et al.
Cell Death Dis
. 2023 Dec;
14(12):799.
PMID: 38057328
HSP90 has emerged as an appealing anti-cancer target. However, HSP90 inhibitors (HSP90i) are characterized by limited clinical utility, primarily due to the resistance acquisition via heat shock response (HSR) induction....
8.
Qin N, Paisana E, Picard D, Leprivier G, Langini M, Custodia C, et al.
J Neurooncol
. 2023 Nov;
165(2):329-342.
PMID: 37976029
Purpose: Primary brain tumors are a leading cause of cancer-related death in children, and medulloblastoma is the most common malignant pediatric brain tumor. The current molecular characterization of medulloblastoma is...
9.
Wagener R, Brandes D, Jung M, Huetzen M, Bergmann A, Panier S, et al.
Int J Cancer
. 2023 Sep;
154(4):607-614.
PMID: 37776287
Genetic predisposition is one of the major risk factors for pediatric cancer, with ~10% of children being carriers of a predisposing germline alteration. It is likely that this is the...
10.
Picard D, Felsberg J, Langini M, Stachura P, Qin N, Macas J, et al.
Acta Neuropathol
. 2023 Sep;
146(4):551-564.
PMID: 37656187
Pilocytic astrocytoma (PA), the most common pediatric brain tumor, is driven by aberrant mitogen-activated protein kinase signaling most commonly caused by BRAF gene fusions or activating mutations. While 5-year overall...