Anja Schrade
Overview
Explore the profile of Anja Schrade including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
177
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Recent Articles
1.
Schrade A, Bujotzek A, Spick C, Wagner M, Goerl J, Wezler X, et al.
Antibodies (Basel)
. 2019 Sep;
8(3).
PMID: 31544851
Bispecific antibodies (bsAbs) with avidity-enhanced specificity can be used to address target cells with increased specificity, ideally binding efficiently to cells that express two cognate antigens, yet not to cells...
2.
Penny G, Cochran R, Pihlajoki M, Kyronlahti A, Schrade A, Hakkinen M, et al.
Reproduction
. 2017 Jul;
154(4):455-467.
PMID: 28710293
Testicular Leydig cells produce androgens essential for proper male reproductive development and fertility. Here, we describe a new Leydig cell ablation model based on Cre/Lox recombination of mouse and ,...
3.
Schrade A, Kyronlahti A, Akinrinade O, Pihlajoki M, Fischer S, Martinez Rodriguez V, et al.
Endocrinology
. 2016 Mar;
157(6):2416-31.
PMID: 26974005
Conditional deletion of Gata4 in Sertoli cells (SCs) of adult mice has been shown to increase permeability of the blood-testis barrier (BTB) and disrupt spermatogenesis. To gain insight into the...
4.
Heikinheimo M, Pihlajoki M, Schrade A, Kyronlahti A, Wilson D
Endocrinology
. 2015 Apr;
156(5):1616-9.
PMID: 25886071
No abstract available.
5.
Schrade A, Kyronlahti A, Akinrinade O, Pihlajoki M, Hakkinen M, Fischer S, et al.
Endocrinology
. 2015 Feb;
156(5):1860-72.
PMID: 25668067
Transcription factor GATA4 is expressed in somatic cells of the mammalian testis. Gene targeting studies in mice have shown that GATA4 is essential for proper differentiation and function of Sertoli...
6.
Rohrig T, Pihlajoki M, Ziegler R, Cochran R, Schrade A, Schillebeeckx M, et al.
Mol Cell Endocrinol
. 2014 Dec;
408:165-77.
PMID: 25498963
Cell fate decisions are integral to zonation and remodeling of the adrenal cortex. Animal models exhibiting ectopic differentiation of gonadal-like cells in the adrenal cortex can shed light on the...
7.
Schillebeeckx M, Pihlajoki M, Gretzinger E, Yang W, Thol F, Hiller T, et al.
Mol Cell Endocrinol
. 2014 Oct;
399:122-30.
PMID: 25289806
Gonadectomy (GDX) induces sex steroid-producing adrenocortical tumors in certain mouse strains and in the domestic ferret. Transcriptome analysis and DNA methylation mapping were used to identify novel genetic and epigenetic...
8.
Parviainen H, Schrade A, Kiiveri S, Prunskaite-Hyyrylainen R, Haglund C, Vainio S, et al.
Pathol Res Pract
. 2013 Jul;
209(8):503-9.
PMID: 23866946
Factors controlling benign and malignant adrenocortical tumorigenesis are largely unknown, but several mouse models suggest an important role for inhibin-alpha (INHA). To show that findings in the mouse are relevant...
9.
Schillebeeckx M, Schrade A, Lobs A, Pihlajoki M, Wilson D, Mitra R
Nucleic Acids Res
. 2013 Apr;
41(11):e116.
PMID: 23589626
DNA methylation is a mechanism for long-term transcriptional regulation and is required for normal cellular differentiation. Failure to properly establish or maintain DNA methylation patterns leads to cell dysfunction and...
10.
Pihlajoki M, Gretzinger E, Cochran R, Kyronlahti A, Schrade A, Hiller T, et al.
Endocrinology
. 2013 Mar;
154(5):1754-67.
PMID: 23471215
Transcription factor GATA6 is expressed in the fetal and adult adrenal cortex and has been implicated in steroidogenesis. To characterize the role of transcription factor GATA6 in adrenocortical development and...