Anja G Teschemacher
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Explore the profile of Anja G Teschemacher including associated specialties, affiliations and a list of published articles.
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42
Citations
1654
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Recent Articles
1.
Theparambil S, Kopach O, Braga A, Nizari S, Hosford P, Sagi-Kiss V, et al.
Nature
. 2024 Jul;
632(8023):139-146.
PMID: 38961289
Brain computation performed by billions of nerve cells relies on a sufficient and uninterrupted nutrient and oxygen supply. Astrocytes, the ubiquitous glial neighbours of neurons, govern brain glucose uptake and...
2.
Belozor O, Vasilev A, Mileiko A, Mosina L, Mikhailov I, Ox D, et al.
Biomed Pharmacother
. 2024 Apr;
174:116526.
PMID: 38574621
Spinocerebellar ataxia type 1 (SCA1) is a debilitating neurodegenerative disorder of the cerebellum and brainstem. Memantine has been proposed as a potential treatment for SCA1. It blocks N-methyl-D-aspartate (NMDA) receptors...
3.
Vaccari-Cardoso B, Antipina M, Teschemacher A, Kasparov S
Brain Sci
. 2023 Jan;
13(1).
PMID: 36672031
Lactate is a universal metabolite produced and released by all cells in the body. Traditionally it was viewed as energy currency that is generated from pyruvate at the end of...
4.
Shuvaev A, Belozor O, Mozhei O, Shuvaev A, Fritsler Y, Khilazheva E, et al.
Cells
. 2022 Jul;
11(14).
PMID: 35883691
Spinocerebellar ataxia type 1 (SCA1) is an intractable progressive neurodegenerative disease that leads to a range of movement and motor defects and is eventually lethal. Purkinje cells (PC) are typically...
5.
Shuvaev A, Belozor O, Mozhei O, Mileiko A, Mosina L, Laletina I, et al.
Brain Sci
. 2022 Apr;
12(4).
PMID: 35448027
Memantine is an FDA approved drug for the treatment of Alzheimer's disease. It reduces neurodegeneration in the hippocampus and cerebral cortex through the inhibition of extrasynaptic NMDA receptors in patients...
6.
Vasilev A, Sofi R, Smith S, Rahman R, Teschemacher A, Kasparov S
Biomedicines
. 2021 Oct;
9(10).
PMID: 34680569
One of the most challenging problems in the treatment of glioblastoma (GBM) is the highly infiltrative nature of the disease. Infiltrating cells that are non-resectable are left behind after debulking...
7.
Vaccari Cardoso B, Barrera I, Mosienko V, Gourine A, Kasparov S, Teschemacher A
Brain Sci
. 2021 Aug;
11(8).
PMID: 34439675
Astrocytes support and modulate neuronal activity through the release of L-lactate. The suggested roles of astrocytic lactate in the brain encompass an expanding range of vital functions, including central control...
8.
Shuvaev A, Belozor O, Mozhei O, Yakovleva D, Potapenko I, Shuvaev A, et al.
Neurobiol Dis
. 2021 Mar;
154:105340.
PMID: 33753288
Bergmann glia (BG) are highly specialized radial astrocytes of the cerebellar cortex, which play a key role in the uptake of synaptic glutamate via the excitatory amino acid transporter EAAT1....
9.
Vaccari Cardoso B, Shevelkin A, Terrillion C, Mychko O, Mosienko V, Kasparov S, et al.
Glia
. 2021 Jan;
69(5):1241-1250.
PMID: 33400321
Astrocytes are in control of metabolic homeostasis in the brain and support and modulate neuronal function in various ways. Astrocyte-derived l-lactate (lactate) is thought to play a dual role as...
10.
Mozhei O, Teschemacher A, Kasparov S
Cancers (Basel)
. 2020 Dec;
12(12).
PMID: 33322507
In this review, we scrutinize the idea of using viral vectors either as cytotoxic agents or gene delivery tools for treatment of glioblastoma multiforme (GBM) in light of the experience...