Alexander V Gourine
Overview
Explore the profile of Alexander V Gourine including associated specialties, affiliations and a list of published articles.
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Articles
127
Citations
4657
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Recent Articles
1.
Non-invasive vagus nerve stimulation and exercise capacity in healthy volunteers: a randomized trial
Ackland G, Patel A, Miller S, Gutierrez Del Arroyo A, Thirugnanasambanthar J, Ravindran J, et al.
Eur Heart J
. 2025 Feb;
PMID: 39969124
Background And Aims: Vagal parasympathetic dysfunction is strongly associated with impaired exercise tolerance, indicating that coordinated autonomic control is essential for optimizing exercise performance. This study tested the hypothesis that...
2.
Wittenberg P, McBryde F, Korsak A, Rodrigues K, Paton J, Marina N, et al.
J Physiol
. 2025 Feb;
PMID: 39924875
Maintaining sufficient cerebral blood flow is critical for brain function. There is evidence that one of the mechanisms that ensure adequate blood flow to the brain involves the regulation of...
3.
Basalay M, Korsak A, He Z, Gourine A, Davidson S, Yellon D
Circ Res
. 2024 Dec;
136(2):229-231.
PMID: 39690446
No abstract available.
4.
Kellett D, Aziz Q, Humphries J, Korsak A, Braga A, Gutierrez Del Arroyo A, et al.
Physiol Genomics
. 2024 Jul;
56(2):167-178.
PMID: 39071113
Heart failure is a major clinical problem, with treatments involving medication, devices, and emerging neuromodulation therapies such as vagus nerve stimulation (VNS). Considering the ongoing interest in using VNS to...
5.
Theparambil S, Kopach O, Braga A, Nizari S, Hosford P, Sagi-Kiss V, et al.
Nature
. 2024 Jul;
632(8023):139-146.
PMID: 38961289
Brain computation performed by billions of nerve cells relies on a sufficient and uninterrupted nutrient and oxygen supply. Astrocytes, the ubiquitous glial neighbours of neurons, govern brain glucose uptake and...
6.
Mascarenhas A, Braga A, Majernikova S, Nizari S, Marletta D, Theparambil S, et al.
J Physiol
. 2024 Jun;
PMID: 38843467
The brain requires an uninterrupted supply of oxygen and nutrients to support the high metabolic needs of billions of nerve cells processing information. In low oxygen conditions, increases in cerebral...
7.
Kellett D, Aziz Q, Humphries J, Korsak A, Braga A, Gutierrez Del Arroyo A, et al.
Physiol Genomics
. 2023 Dec;
56(2):167-178.
PMID: 38047311
Heart failure is a major clinical problem, with treatments involving medication, devices, and emerging neuromodulation therapies such as vagus nerve stimulation (VNS). Considering the ongoing interest in using VNS to...
8.
Christie I, Theparambil S, Braga A, Doronin M, Hosford P, Brazhe A, et al.
Cell Rep
. 2023 Dec;
42(12):113514.
PMID: 38041814
During hypoxia, increases in cerebral blood flow maintain brain oxygen delivery. Here, we describe a mechanism of brain oxygen sensing that mediates the dilation of intraparenchymal cerebral blood vessels in...
9.
SheikhBahaei S, Marina N, Rajani V, Kasparov S, Funk G, Smith J, et al.
J Physiol
. 2023 Sep;
602(1):223-240.
PMID: 37742121
Current models of respiratory CO chemosensitivity are centred around the function of a specific population of neurons residing in the medullary retrotrapezoid nucleus (RTN). However, there is significant evidence suggesting...
10.
Gourine A, Theparambil S
J Physiol
. 2023 Aug;
601(18):4171-4172.
PMID: 37598302
No abstract available.