Anja F Hohmann
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Explore the profile of Anja F Hohmann including associated specialties, affiliations and a list of published articles.
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7
Citations
438
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Recent Articles
1.
Schlabach M, Lin S, Collester Z, Wrocklage C, Shenker S, Calnan C, et al.
J Clin Invest
. 2023 Dec;
133(24).
PMID: 38099496
Cell therapies such as tumor-infiltrating lymphocyte (TIL) therapy have shown promise in the treatment of patients with refractory solid tumors, with improvement in response rates and durability of responses nevertheless...
2.
Hohmann A, Martin L, Minder J, Roe J, Shi J, Steurer S, et al.
Nat Chem Biol
. 2016 Jul;
12(9):672-9.
PMID: 27376689
Here we show that acute myeloid leukemia (AML) cells require the BRD9 subunit of the SWI-SNF chromatin-remodeling complex to sustain MYC transcription, rapid cell proliferation and a block in differentiation....
3.
Bhagwat A, Roe J, Mok B, Hohmann A, Shi J, Vakoc C
Cell Rep
. 2016 Apr;
15(3):519-530.
PMID: 27068464
The bromodomain and extraterminal (BET) protein BRD4 can physically interact with the Mediator complex, but the relevance of this association to the therapeutic effects of BET inhibitors in cancer is...
4.
Martin L, Koegl M, Bader G, Cockcroft X, Fedorov O, Fiegen D, et al.
J Med Chem
. 2016 Feb;
59(10):4462-75.
PMID: 26914985
Components of the chromatin remodelling switch/sucrose nonfermentable (SWI/SNF) complex are recurrently mutated in tumors, suggesting that altering the activity of the complex plays a role in oncogenesis. However, the role...
5.
Wang E, Kawaoka S, Roe J, Shi J, Hohmann A, Xu Y, et al.
Elife
. 2015 Apr;
4:e06377.
PMID: 25919951
Most mammalian transcription factors (TFs) and cofactors occupy thousands of genomic sites and modulate the expression of large gene networks to implement their biological functions. In this study, we describe...
6.
Hohmann A, Vakoc C
Trends Genet
. 2014 Jun;
30(8):356-63.
PMID: 24932742
SWI/SNF is a multisubunit chromatin-remodeling complex that performs fundamental roles in gene regulation, cell lineage specification, and organismal development. Mutations that inactivate SWI/SNF subunits are found in nearly 20% of...
7.
Guzadhur L, Pearcey S, Duehmke R, Jeevaratnam K, Hohmann A, Zhang Y, et al.
Pflugers Arch
. 2010 Jun;
460(3):593-601.
PMID: 20552221
Recent studies have reported that human mutations in Nav1.5 predispose to early age onset atrial arrhythmia. The present experiments accordingly assess atrial arrhythmogenicity in aging Scn5a+/KPQ mice modeling long QT3...