Anja Bremm
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Explore the profile of Anja Bremm including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
997
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Recent Articles
1.
Bajdzienko J, Bremm A
J Cell Sci
. 2024 May;
137(9).
PMID: 38752931
Peroxisomes are highly plastic organelles that are involved in several metabolic processes, including fatty acid oxidation, ether lipid synthesis and redox homeostasis. Their abundance and activity are dynamically regulated in...
2.
Mende H, Khatri A, Lange C, Poveda-Cuevas S, Tascher G, Covarrubias-Pinto A, et al.
Cell Rep
. 2023 Nov;
42(12):113484.
PMID: 37999976
The nucleolar scaffold protein NPM1 is a multifunctional regulator of cellular homeostasis, genome integrity, and stress response. NPM1 mutations, known as NPM1c variants promoting its aberrant cytoplasmic localization, are the...
3.
Hertel A, Eimer S, Bremm A
Autophagy
. 2023 Feb;
19(8):2406-2407.
PMID: 36847417
Among the various signals governing autophagy, ubiquitination plays a critical role both by controlling the stability of upstream regulators or components of macroautophagy/autophagy pathways and by facilitating the recruitment of...
4.
de Oliveira Freitas Machado C, Schafranek M, Bruggemann M, Hernandez Canas M, Keller M, Di Liddo A, et al.
Nucleic Acids Res
. 2023 Jan;
51(2):870-890.
PMID: 36620874
Hypoxia induces massive changes in alternative splicing (AS) to adapt cells to the lack of oxygen. Here, we identify the splicing factor SRSF6 as a key factor in the AS...
5.
Hertel A, Alves L, Dutz H, Tascher G, Bonn F, Kaulich M, et al.
Cell Rep
. 2022 Dec;
41(10):111653.
PMID: 36476874
The endosomal-lysosomal system is a series of organelles in the endocytic pathway that executes trafficking and degradation of proteins and lipids and mediates the internalization of nutrients and growth factors...
6.
Basic M, Hertel A, Bajdzienko J, Bonn F, Tellechea M, Stolz A, et al.
J Biol Chem
. 2021 Oct;
297(5):101263.
PMID: 34600886
Autophagy is a major cellular quality control system responsible for the degradation of proteins and organelles in response to stress and damage to maintain homeostasis. Ubiquitination of autophagy-related proteins or...
7.
Bremm A
Sci Signal
. 2020 Oct;
13(654).
PMID: 33082290
Precise control of the activity and abundance of ubiquitin-conjugating enzymes (E2s) ensures fidelity in ubiquitin chain synthesis. In this issue of , Liess demonstrate that the human anaphase-promoting complex (APC/C)-associated...
8.
Mader J, Huber J, Bonn F, Dotsch V, Rogov V, Bremm A
J Biol Chem
. 2020 Jan;
295(8):2160-2174.
PMID: 31937588
Deubiquitinases (DUBs) are vital for the regulation of ubiquitin signals, and both catalytic activity of and target recruitment by DUBs need to be tightly controlled. Here, we identify asparagine hydroxylation...
9.
Wegner M, Diehl V, Bittl V, de Bruyn R, Wiechmann S, Matthess Y, et al.
Elife
. 2019 Mar;
8.
PMID: 30838976
Current technologies used to generate CRISPR/Cas gene perturbation reagents are labor intense and require multiple ligation and cloning steps. Furthermore, increasing gRNA sequence diversity negatively affects gRNA distribution, leading to...
10.
Fottner M, Brunner A, Bittl V, Horn-Ghetko D, Jussupow A, Kaila V, et al.
Nat Chem Biol
. 2019 Feb;
15(3):276-284.
PMID: 30770915
Post-translational modification of proteins with ubiquitin and ubiquitin-like proteins (Ubls) is central to the regulation of eukaryotic cellular processes. Our ability to study the effects of ubiquitylation, however, is limited...