Anita Schildknecht
Overview
Explore the profile of Anita Schildknecht including associated specialties, affiliations and a list of published articles.
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11
Citations
474
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Recent Articles
1.
B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity
Rahbar R, Lin A, Ghazarian M, Yau H, Paramathas S, Lang P, et al.
Cancer Immunol Res
. 2014 Dec;
3(2):184-95.
PMID: 25527357
The B7 family plays a critical role in both positive and negative regulation of immune responses by engaging a variety of receptors on lymphocytes. Importantly, blocking coinhibitory molecules using antibodies...
2.
Schildknecht A, Brauer S, Brenner C, Lahl K, Schild H, Sparwasser T, et al.
Proc Natl Acad Sci U S A
. 2009 Dec;
107(1):199-203.
PMID: 20018763
Peripheral T-cell tolerance is thought to significantly contribute to the prevention of autoimmunity, and it has been shown that antigen-presenting steady-state dendritic cells efficiently induce peripheral tolerance. We previously showed...
3.
Wueest S, Rapold R, Schumann D, Rytka J, Schildknecht A, Nov O, et al.
J Clin Invest
. 2009 Dec;
120(1):191-202.
PMID: 19955656
Adipose tissue inflammation is linked to the pathogenesis of insulin resistance. In addition to exerting death-promoting effects, the death receptor Fas (also known as CD95) can activate inflammatory pathways in...
4.
Lin A, Schildknecht A, Nguyen L, Ohashi P
Immunol Lett
. 2009 Sep;
127(2):77-84.
PMID: 19778555
Dendritic cells (DCs) are professional antigen presenting cells with the ability to either initiate or prevent the induction of antigen-specific T cell responses. The conventional DC-centric paradigm of DC-T cell...
5.
Schildknecht A, Probst H, McCoy K, Miescher I, Brenner C, Leone D, et al.
Eur J Immunol
. 2009 May;
39(6):1505-15.
PMID: 19462379
Auto-reactivity of T cells is largely prevented by central and peripheral tolerance. Nevertheless, immunization with certain self-antigens emulsified in CFA induces autoimmunity in rodents, suggesting that tolerance to some self-antigens...
6.
Keller A, Schildknecht A, Xiao Y, van den Broek M, Borst J
Immunity
. 2008 Dec;
29(6):934-46.
PMID: 19062317
Steady-state dendritic cells (DCs) maintain peripheral T cell tolerance, whereas mature DCs generate immunity. CD70 is a costimulatory ligand acquired upon DC maturation. To determine its impact on T cell...
7.
Kranich J, Krautler N, Heinen E, Polymenidou M, Bridel C, Schildknecht A, et al.
J Exp Med
. 2008 May;
205(6):1293-302.
PMID: 18490487
The secreted phosphatidylserine-binding protein milk fat globule epidermal growth factor 8 (Mfge8) mediates engulfment of apoptotic germinal center B cells by tingible-body macrophages (TBMphis). Impairment of this process can contribute...
8.
Lilienfeld B, Schildknecht A, Imbach L, Mueller N, Schneider M, Seebach J
Xenotransplantation
. 2008 May;
15(2):136-44.
PMID: 18447887
Background: Natural killer (NK) cells participate in the immune response against solid organ allo- and xenografts and are tightly regulated through signals mediated by inhibiting and activating receptors expressed on...
9.
Schildknecht A, Welti S, Geuking M, Hangartner L, van den Broek M
J Immunol
. 2008 Feb;
180(5):3113-21.
PMID: 18292534
CD8+ T cells are crucial for the control of intracellular pathogens such as viruses and some bacteria. Using lymphocytic choriomeningitis virus (LCMV) infection of mice--the prototypic arenavirus evolutionarily closely related...
10.
Fink K, Manjarrez-Orduno N, Schildknecht A, Weber J, Senn B, Zinkernagel R, et al.
J Immunol
. 2007 Oct;
179(9):5877-85.
PMID: 17947661
Germinal centers are structures that promote humoral memory cell formation and affinity maturation, but the triggers for their development are not entirely clear. Activated extrafollicular B cells can form IgM-producing...