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Anita Rudy

Explore the profile of Anita Rudy including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 125
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Recent Articles
1.
Weir M, Pergola P, Agarwal R, Fink J, Kopyt N, Singh A, et al.
Am J Nephrol . 2017 Oct; 46(5):364-370. PMID: 29084409
Background: HX575 (biosimilar epoetin alfa) was approved in Europe in 2007 for the treatment of chronic kidney disease (CKD)-related anemia. This study assessed the clinical equivalence of HX575 with the...
2.
Casadevall N, Dobronravov V, Eckardt K, Erturk S, Martynyuk L, Schmitt S, et al.
Clin Nephrol . 2017 Aug; 88(10):190-197. PMID: 28766493
Aim: To assess the safety and immunogenicity of subcutaneous (SC) HX575 (epoetin-α) in dialysis- and nondialysis-dependent adult patients with chronic kidney disease (CKD). Methods: Open-label, single-arm, multicenter study in patients...
3.
Harbeck N, Lipatov O, Frolova M, Udovitsa D, Topuzov E, Ganea-Motan D, et al.
Future Oncol . 2016 Mar; 12(11):1359-67. PMID: 27020170
Aim: This randomized, double-blind trial compared proposed biosimilar LA-EP2006 with reference pegfilgrastim in women receiving chemotherapy for breast cancer (PROTECT-1). Patients & Methods: Women (≥18 years) were randomized to receive...
4.
Hoffmann R, von Schwarzenberg K, Lopez-Anton N, Rudy A, Wanner G, Dirsch V, et al.
Biochem Pharmacol . 2011 Jun; 82(5):453-63. PMID: 21669190
Evasion of cell death by overexpression of anti-apoptotic proteins, such as Bcl-2, is commonly observed in cancer cells leading to a lack of response to chemotherapy. Hence, there is a...
5.
Pfisterer P, Shen C, Nikolovska-Coleska Z, Schyschka L, Schuster D, Rudy A, et al.
Bioorg Med Chem . 2010 Nov; 19(2):1002-9. PMID: 21087868
Targeting the baculoviral inhibitor of apoptosis proteins repeat (BIR) 3 of X-linked inhibitor of apoptosis proteins (XIAP) represents an innovative strategy for the design of chemosensitizers. Acylated flavonol monorhamnosides (AFMR)...
6.
Pfisterer P, Rollinger J, Schyschka L, Rudy A, Vollmar A, Stuppner H
Planta Med . 2010 May; 76(15):1698-700. PMID: 20446243
Extracts of the traditional medicinal herb Andrographis paniculata and its main constituents are described in the literature as showing anticancer activity. The aim of this study was to isolate the...
7.
Rothmeier A, Schneiders U, Wiedmann R, Ischenko I, Bruns C, Rudy A, et al.
Int J Cancer . 2010 Feb; 127(5):1096-105. PMID: 20143389
Treatment of pancreatic cancer remains a major challenge and new anticancer drugs are urgently required. Our study presents the marine natural compound spongistatin 1 as a promising experimental drug. Spongistatin...
8.
Schneiders U, Schyschka L, Rudy A, Vollmar A
Mol Cancer Ther . 2009 Oct; 8(10):2914-25. PMID: 19808980
Spongistatin 1, a marine experimental substance with chemotherapeutic potential, induces apoptosis and inhibits clonogenic survival of MCF-7 cells. Regarding the apoptotic signaling pathways of spongistatin 1, we present two major...
9.
Rudy A, Lopez-Anton N, Dirsch V, Vollmar A
J Nat Prod . 2008 Feb; 71(3):482-6. PMID: 18257532
The cephalostatins, bis-steroidal natural products from the marine tube worm Cephalodiscus gilchristi, were isolated by Dr. G. R. Pettit and his group. These compounds show a unique cytotoxicity profile in...
10.
Lopez-Anton N, Rudy A, Barth N, Schmitz M, Schmitz L, Pettit G, et al.
J Biol Chem . 2006 Sep; 281(44):33078-86. PMID: 16945918
Cephalostatin 1, a bis-steroidal marine natural product, has been reported to induce apoptosis without the requirement of an active caspase-8 or mitochondrial cytochrome c release and apoptosome formation. Here we...