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Anita Q Gomes

Explore the profile of Anita Q Gomes including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 594
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Recent Articles
1.
Inacio D, Amado T, Pamplona A, Sobral D, Cunha C, Santos R, et al.
Nat Immunol . 2025 Jan; 26(3):497-510. PMID: 39881001
γδ T cells producing either interleukin-17A (γδ cells) or interferon-γ (γδ cells) are generated in the mouse thymus, but the molecular regulators of their peripheral functions are not fully characterized....
2.
Gordino G, Costa-Pereira S, Corredeira P, Alves P, Costa L, Gomes A, et al.
EMBO Rep . 2021 Nov; 23(1):e52234. PMID: 34821000
γδ T cells are a conserved population of lymphocytes that contributes to anti-tumor responses through its overt type 1 inflammatory and cytotoxic properties. We have previously shown that human γδ...
3.
Fiala G, Gomes A, Silva-Santos B
Immunol Rev . 2020 Nov; 298(1):47-60. PMID: 33191519
The contributions of γδ T cells to immune (patho)physiology in many pre-clinical mouse models have been associated with their rapid and abundant provision of two critical cytokines, interferon-γ (IFN-γ) and...
4.
Amado T, Amorim A, Enguita F, Romero P, Inacio D, de Miranda M, et al.
J Mol Med (Berl) . 2020 Feb; 98(2):309-320. PMID: 32002568
CD8 T cells are key players in immunity against intracellular infections and tumors. The main cytokine associated with these protective responses is interferon-γ (IFN-γ), whose production is known to be...
5.
Ribot J, Neres R, Zuzarte-Luis V, Gomes A, Mancio-Silva L, Mensurado S, et al.
Proc Natl Acad Sci U S A . 2019 Apr; 116(20):9979-9988. PMID: 31028144
Cerebral malaria (CM) is a major cause of death due to infection. Both parasite and host factors contribute to the onset of CM, but the precise cellular and molecular mechanisms...
6.
Schmolka N, Papotto P, Romero P, Amado T, Enguita F, Amorim A, et al.
Sci Immunol . 2018 May; 3(23). PMID: 29728425
γδ T cells are major providers of proinflammatory cytokines. They are preprogrammed in the mouse thymus into distinct subsets producing either interleukin-17 (IL-17) or interferon-γ (IFN-γ), which segregate with CD27...
7.
Inacio D, Amado T, Silva-Santos B, Gomes A
Cancer Lett . 2018 Apr; 427:63-73. PMID: 29679611
The differentiation of effector T cells is a tightly regulated process that relies on the selective expression of lineage-defining master regulators that orchestrate unique transcriptional programs, including the production of...
8.
Amado T, Schmolka N, Metwally H, Silva-Santos B, Gomes A
Eur J Immunol . 2015 Apr; 45(6):1584-95. PMID: 25865116
microRNA (miRNA) mediated regulation of protein expression has emerged as an important mechanism in T-cell physiology, from development and survival to activation, proliferation, and differentiation. One of the major classes...
9.
Moutinho M, Nunes M, Gomes A, Gama M, Cedazo-Minguez A, Rodrigues C, et al.
Mol Neurobiol . 2014 Aug; 51(3):1489-503. PMID: 25084760
The neuronal-specific cholesterol 24S-hydroxylase (CYP46A1) is important for brain cholesterol elimination. Cyp46a1 null mice exhibit severe deficiencies in learning and hippocampal long-term potentiation, suggested to be caused by a decrease...
10.
Viegas C, Gomes A, Abegao J, Sabino R, Graca T, Viegas S
J Toxicol Environ Health A . 2014 Feb; 77(1-3):57-68. PMID: 24555647
Organic waste is a rich substrate for microbial growth, and because of that, workers from waste industry are at higher risk of exposure to bioaerosols. This study aimed to assess...