Anita Kotar
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Explore the profile of Anita Kotar including associated specialties, affiliations and a list of published articles.
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17
Citations
143
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Recent Articles
1.
Sahoo B, Kocman V, Clark N, Myers N, Deng X, Wong E, et al.
Nucleic Acids Res
. 2024 Apr;
52(8):4702-4722.
PMID: 38572746
The SERF family of proteins were originally discovered for their ability to accelerate amyloid formation. Znf706 is an uncharacterized protein whose N-terminus is homologous to SERF proteins. We show here...
2.
Sahoo B, Kocman V, Clark N, Myers N, Deng X, Wong E, et al.
bioRxiv
. 2023 Oct;
PMID: 37790366
The SERF family of proteins were originally discovered for their ability to accelerate amyloid formation. Znf706 is an uncharacterized protein whose N-terminus is homologous to SERF proteins. We show here...
3.
Ma S, Kotar A, Hall I, Grote S, Rouskin S, Keane S
Proc Natl Acad Sci U S A
. 2023 Sep;
120(39):e2300527120.
PMID: 37725636
As an essential posttranscriptional regulator of gene expression, microRNA (miRNA) levels must be strictly maintained. The biogenesis of many miRNAs is mediated by trans-acting protein partners through a variety of...
4.
Ma S, Kotar A, Grote S, Rouskin S, Keane S
bioRxiv
. 2023 Jan;
PMID: 36711709
As an essential post-transcriptional regulator of gene expression, microRNA (miR) levels must be strictly maintained. The biogenesis of many, but not all, miRs is mediated by trans-acting protein partners through...
5.
Evans L, Kotar A, Valentini M, Filloux A, Jamshidi S, Plavec J, et al.
RSC Chem Biol
. 2023 Jan;
4(1):94-100.
PMID: 36685252
A number of Gram-negative bacteria such as are becoming resistant to front-line antibiotics. Consequently, there is a pressing need to find alternative bio-molecular targets for the development of new drugs....
6.
Kotar A, Ma S, Keane S
Biophys Chem
. 2022 Feb;
283:106763.
PMID: 35114594
MicroRNAs (miRNAs) are important regulators of post-transcriptional gene expression. Mature miRNAs are generated from longer transcripts (primary, pri- and precursor, pre-miRNAs) through a series of highly coordinated enzymatic processing steps....
7.
Chemical Modulation of DNA Replication along G-Quadruplex Based on Topology-Dependent Ligand Binding
Takahashi S, Kotar A, Tateishi-Karimata H, Bhowmik S, Wang Z, Chang T, et al.
J Am Chem Soc
. 2021 Sep;
143(40):16458-16469.
PMID: 34554731
Ligands that bind to and stabilize guanine-quadruplex (G4) structures to regulate DNA replication have therapeutic potential for cancer and neurodegenerative diseases. Because there are several G4 topologies, ligands that bind...
8.
Liu Y, Kotar A, Hodges T, Abdallah K, Taleb M, Bitterman B, et al.
Biomol NMR Assign
. 2021 Aug;
15(2):479-490.
PMID: 34449019
RNAs play myriad functional and regulatory roles in the cell. Despite their significance, three-dimensional structure elucidation of RNA molecules lags significantly behind that of proteins. NMR-based studies are often rate-limited...
9.
Pirc K, Hodnik V, Snoj T, Lenarcic T, Caserman S, Podobnik M, et al.
PLoS Pathog
. 2021 Apr;
17(4):e1009477.
PMID: 33857257
The lack of efficient methods to control the major diseases of crops most important to agriculture leads to huge economic losses and seriously threatens global food security. Many of the...
10.
Kotar A, Foley H, Baughman K, Keane S
Methods
. 2020 Jan;
183:93-107.
PMID: 31972224
NMR spectroscopy is a key technique that has significantly advanced our understanding of RNA structure and dynamics. However, determination of large RNA structures by NMR spectroscopy remains a significant technical...