Anissa Kempf
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Explore the profile of Anissa Kempf including associated specialties, affiliations and a list of published articles.
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8
Citations
354
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Recent Articles
1.
Hartmann C, Kempf A
Curr Opin Neurobiol
. 2023 Jun;
81:102733.
PMID: 37390796
The function of sleep remains one of biology's biggest mysteries. A solution to this problem is likely to come from a better understanding of sleep homeostasis, and in particular of...
2.
Kempf A, Song S, Talbot C, Miesenbock G
Nature
. 2019 Mar;
568(7751):230-234.
PMID: 30894743
The essential but enigmatic functions of sleep must be reflected in molecular changes sensed by the brain's sleep-control systems. In the fruitfly Drosophila, about two dozen sleep-inducing neurons with projections...
3.
Donlea J, Pimentel D, Talbot C, Kempf A, Omoto J, Hartenstein V, et al.
Neuron
. 2018 Jan;
97(2):378-389.e4.
PMID: 29307711
Sleep-promoting neurons in the dorsal fan-shaped body (dFB) of Drosophila are integral to sleep homeostasis, but how these cells impose sleep on the organism is unknown. We report that dFB...
4.
Kempf A, Boda E, Kwok J, Fritz R, Grande V, Kaelin A, et al.
Dev Cell
. 2017 Sep;
43(1):24-34.e5.
PMID: 28943240
Heparan sulfate proteoglycans (HSPGs) critically modulate adhesion-, growth-, and migration-related processes. Here, we show that the transmembrane protein, Nogo-A, inhibits neurite outgrowth and cell spreading in neurons and Nogo-A-responsive cell...
5.
Kempf A, Tews B, Arzt M, Weinmann O, Obermair F, Pernet V, et al.
PLoS Biol
. 2014 Jan;
12(1):e1001763.
PMID: 24453941
Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite growth and synaptic plasticity via two extracellular domains: Nogo-66 and Nogo-A-Δ20. Receptors transducing Nogo-A-Δ20 signaling remained elusive...
6.
Kempf A, Montani L, Petrinovic M, Schroeter A, Weinmann O, Patrignani A, et al.
Eur J Neurosci
. 2013 Oct;
38(11):3567-79.
PMID: 24103058
Adult central nervous system axons show restricted growth and regeneration properties after injury. One of the underlying mechanisms is the activation of the Nogo-A/Nogo receptor (NgR1) signaling pathway. Nogo-A knockout...
7.
Kempf A, Schwab M
Physiology (Bethesda)
. 2013 May;
28(3):151-63.
PMID: 23636261
Nogo-A was initially discovered as a myelin-associated growth inhibitory protein limiting axonal regeneration after central nervous system (CNS) injury. This review summarizes current knowledge on how myelin and neuronal Nogo-A...
8.
Montani L, Gerrits B, Gehrig P, Kempf A, Dimou L, Wollscheid B, et al.
J Biol Chem
. 2009 Feb;
284(16):10793-807.
PMID: 19208621
Nogo-A has been extensively studied as a myelin-associated neurite outgrowth inhibitor in the lesioned adult central nervous system. However, its role in the intact central nervous system has not yet...