Peter Spies
Overview
Explore the profile of Peter Spies including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
225
Followers
0
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Recent Articles
1.
Dirscherl L, Merz L, Kobras R, Spies P, Frutiger A, Gatterdam V, et al.
Biosensors (Basel)
. 2025 Feb;
15(2).
PMID: 39996969
Characterizing biomolecular receptor-ligand interactions is critical for research and development. However, performing analyses in complex, biologically relevant matrices, such as serum, remains challenging due to non-specific binding that often impairs...
2.
Hug M, Keller S, Marty T, Gygax D, Meinel D, Spies P, et al.
HLA
. 2023 May;
102(3):278-300.
PMID: 37191252
Organs transplanted across donor-specific HLA antibodies (DSA) are associated with a variety of clinical outcomes, including a high risk of acute kidney graft rejection. Unfortunately, the currently available assays to...
3.
Zimmermann I, Egloff P, Hutter C, Arnold F, Stohler P, Bocquet N, et al.
Elife
. 2018 May;
7.
PMID: 29792401
Mechanistic and structural studies of membrane proteins require their stabilization in specific conformations. Single domain antibodies are potent reagents for this purpose, but their generation relies on immunizations, which impedes...
4.
Tobola A, Leutheuser H, Pollak M, Spies P, Hofmann C, Weigand C, et al.
IEEE J Biomed Health Inform
. 2017 Jun;
22(1):15-22.
PMID: 28574370
Wearable health sensors are about to change our health system. While several technological improvements have been presented to enhance performance and energy-efficiency, battery runtime is still a critical concern for...
5.
Kempf A, Tews B, Arzt M, Weinmann O, Obermair F, Pernet V, et al.
PLoS Biol
. 2014 Jan;
12(1):e1001763.
PMID: 24453941
Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite growth and synaptic plasticity via two extracellular domains: Nogo-66 and Nogo-A-Δ20. Receptors transducing Nogo-A-Δ20 signaling remained elusive...
6.
Spies P, Mueller R, Chen G, Gygax D
Anal Biochem
. 2009 Sep;
397(1):48-52.
PMID: 19778520
In this article, we describe a new enzyme-linked immunosorbent assay (ELISA) setup to improve the sensitivity of commercial or homemade ELISAs. In the new ELISA setup, an IMAPlate 5RC96, a...
7.
Rich R, Papalia G, Flynn P, Furneisen J, Quinn J, Klein J, et al.
Anal Biochem
. 2009 Jan;
386(2):194-216.
PMID: 19133223
To explore the variability in biosensor studies, 150 participants from 20 countries were given the same protein samples and asked to determine kinetic rate constants for the interaction. We chose...
8.
Spies P, Chen G, Gygax D
Anal Biochem
. 2008 Jul;
382(1):35-9.
PMID: 18655766
A miniaturized enzyme-linked immunosorbent assay (ELISA) with a reaction volume of 5 microl for human transferrin quantification has successfully been developed using an intelligent multifunctional analytical plate (IMAPlate 5RC96), the...