Angharad E Fenton-May
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Explore the profile of Angharad E Fenton-May including associated specialties, affiliations and a list of published articles.
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7
Citations
357
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Recent Articles
1.
Gondim M, Sherrill-Mix S, Bibollet-Ruche F, Russell R, Trimboli S, Smith A, et al.
Sci Transl Med
. 2021 Jan;
13(576).
PMID: 33441429
Type 1 interferons (IFN-I) are potent innate antiviral effectors that constrain HIV-1 transmission. However, harnessing these cytokines for HIV-1 cure strategies has been hampered by an incomplete understanding of their...
2.
Hertoghs N, Nijmeijer B, van Teijlingen N, Fenton-May A, Kaptein T, van Hamme J, et al.
PLoS One
. 2019 Dec;
14(12):e0226651.
PMID: 31856198
A single HIV-1 variant establishes infection of the host after sexual contact. Identifying the phenotypic characteristics of these Transmitted Founder (T/F) viruses is important to understand the restriction mechanisms during...
3.
Deymier M, Ende Z, Fenton-May A, Dilernia D, Kilembe W, Allen S, et al.
PLoS Pathog
. 2015 Sep;
11(9):e1005154.
PMID: 26378795
Heterosexual transmission of HIV-1 is characterized by a genetic bottleneck that selects a single viral variant, the transmitted/founder (TF), during most transmission events. To assess viral characteristics influencing HIV-1 transmission,...
4.
Fenton-May A, Dibben O, Emmerich T, Ding H, Pfafferott K, Aasa-Chapman M, et al.
Retrovirology
. 2013 Dec;
10:146.
PMID: 24299076
Background: Following mucosal human immunodeficiency virus type 1 (HIV-1) transmission, type 1 interferons (IFNs) are rapidly induced at sites of initial virus replication in the mucosa and draining lymph nodes....
5.
Watson A, Lebedev A, Hall B, Fenton-May A, Vagin A, Dejnirattisai W, et al.
J Biol Chem
. 2011 May;
286(27):24208-18.
PMID: 21566123
The human C-type lectin-like molecule CLEC5A is a critical macrophage receptor for dengue virus. The binding of dengue virus to CLEC5A triggers signaling through the associated adapter molecule DAP12, stimulating...
6.
Watson A, Christou C, James J, Fenton-May A, Moncayo G, Mistry A, et al.
Biochemistry
. 2009 Oct;
48(46):10988-96.
PMID: 19824697
The platelet receptor CLEC-2 binds to the snake venom toxin rhodocytin and the tumor cell surface protein podoplanin. Binding of either of these ligands promotes phosphorylation of a single tyrosine...
7.
Christou C, Pearce A, Watson A, Mistry A, Pollitt A, Fenton-May A, et al.
Biochem J
. 2008 Jan;
411(1):133-40.
PMID: 18215137
We have recently shown that the C-type lectin-like receptor, CLEC-2, is expressed on platelets and that it mediates powerful platelet aggregation by the snake venom toxin rhodocytin. In addition, we...