Angelique B van t Wout
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Explore the profile of Angelique B van t Wout including associated specialties, affiliations and a list of published articles.
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38
Citations
1227
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Recent Articles
1.
Koelink P, Bloemendaal F, Li B, Westera L, Vogels E, van Roest M, et al.
Gut
. 2019 Sep;
69(6):1053-1063.
PMID: 31506328
Objective: Macrophage interleukin (IL)-10 signalling plays a critical role in the maintenance of a regulatory phenotype that prevents the development of IBD. We have previously found that anti-tumour necrosis factor...
2.
Gilman M, Furmanova-Hollenstein P, Pascual G, van t Wout A, Langedijk J, McLellan J
Nat Commun
. 2019 May;
10(1):2105.
PMID: 31068578
The respiratory syncytial virus (RSV) F glycoprotein is a class I fusion protein that mediates viral entry and is a major target of neutralizing antibodies. Structures of prefusion forms of...
3.
Zhang X, Li J, Krautkramer K, Badri M, Battaglia T, Borbet T, et al.
Elife
. 2018 Jul;
7.
PMID: 30039798
The early-life intestinal microbiota plays a key role in shaping host immune system development. We found that a single early-life antibiotic course (1PAT) accelerated type 1 diabetes (T1D) development in...
4.
Koelink P, Wildenberg M, Stitt L, Feagan B, Koldijk M, van t Wout A, et al.
J Crohns Colitis
. 2018 Apr;
12(7):794-803.
PMID: 29608662
Background And Aims: Although several endoscopic and histopathologic indices are available for evaluating the severity of inflammation in mouse models of colitis, the reliability of these scoring instruments is unknown....
5.
Jones H, Ritschel T, Pascual G, Brakenhoff J, Keogh E, Furmanova-Hollenstein P, et al.
PLoS Pathog
. 2018 Mar;
14(3):e1006935.
PMID: 29509814
Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections in infants and the elderly, and yet there remains no effective treatment or vaccine. The surface...
6.
Booiman T, Loukachov V, van Dort K, van t Wout A, Kootstra N
PLoS One
. 2015 Dec;
10(12):e0144229.
PMID: 26641855
Background: Transcription of the HIV-1 provirus is regulated by both viral and host proteins and is very important in the context of viral latency. In latently infected cells, viral gene...
7.
Phosphodiesterase 8a supports HIV-1 replication in macrophages at the level of reverse transcription
Booiman T, Cobos Jimenez V, van Dort K, van t Wout A, Kootstra N
PLoS One
. 2014 Oct;
9(10):e109673.
PMID: 25295610
Background: HIV-1 infected macrophages play a key role in HIV-1 infection. Even during anti-retroviral treatment, macrophages keep producing virus due to suboptimal tissue penetration and reduced efficacy of antiretrovirals. It...
8.
Gijsbers E, van Sighem A, Harskamp A, Welkers M, de Wolf F, Brinkman K, et al.
PLoS One
. 2013 Oct;
8(10):e76255.
PMID: 24098454
The emergence of CXCR4-using HIV variants (X4-HIV) is associated with accelerated disease progression in the absence of antiretroviral therapy. However, the effect of X4-HIV variants on the treatment response remains...
9.
Rotger M, Glass T, Junier T, Lundgren J, Neaton J, Poloni E, et al.
Clin Infect Dis
. 2013 Mar;
57(1):112-21.
PMID: 23532479
Background: Persons infected with human immunodeficiency virus (HIV) have increased rates of coronary artery disease (CAD). The relative contribution of genetic background, HIV-related factors, antiretroviral medications, and traditional risk factors...
10.
Poon A, Swenson L, Bunnik E, Edo-Matas D, Schuitemaker H, van t Wout A, et al.
PLoS Comput Biol
. 2012 Nov;
8(11):e1002753.
PMID: 23133358
At the early stage of infection, human immunodeficiency virus (HIV)-1 predominantly uses the CCR5 coreceptor for host cell entry. The subsequent emergence of HIV variants that use the CXCR4 coreceptor...